Results 111 to 120 of about 10,473,577 (342)

Observable phenomena that reveal medical students' clinical reasoning ability during expert assessment of their history taking: a qualitative study

BMC Medical Education, 2017
During their clerkships, medical students are meant to expand their clinical reasoning skills during their patient encounters. Observation of these encounters could reveal important information on the students’ clinical reasoning abilities, especially ...
C. M. Haring, B. M. Cools, P. V. van Gurp, J. V. D. van der Meer, C. Postma   +4 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Family history‐taking practices and genetic confidence in primary and tertiary care providers for childhood cancer survivors

Pediatric Blood & Cancer, 2018
There is growing impetus for increased genetic screening in childhood cancer survivors. Family history‐taking is a critical first step in determining survivors’ suitability.
C. Wakefield, Veronica F. Quinn, J. Fardell, C. Signorelli, K. Tucker, A. Patenaude, D. Malkin, Thomas Walwyn, F. Alvaro, R. Cohn   +9 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Clues to Bradycardia in a Psychiatric Patient can be Revealed by Good History-Taking: A Case Report and Literature Review

, 2022
Mohammad Abu-Abaa, Maryam Al-Mohammed, Aliaa Mousa   +2 more
openalex   +2 more sources

Simulated patients’ experience of adopting telesimulation for history taking during a pandemic [PDF]

, 2021
Kirsty Freeman, Weiren Wilson Xin, Claire Ann Canning   +2 more
openalex   +1 more source

Loading Chekhov’s Gun in 9-Times: The Fundamental Disconnect in Historical Interpretation [PDF]

, 2013
Thursday night brings into Gettysburg an avalanche of historians (both public and academic) to discuss the Future of Civil War History for a whole weekend.
Rudy, John M.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Acute Ataxia in Children – A Series of Cases to Emphasize the Clinical Approach

MedEdPORTAL, 2011
Introduction This module was developed to help medical students, residents, and fellows learn how to approach the evaluation of children with acute ataxia.
Maria Weimer, Robin English
doaj   +1 more source