Results 111 to 120 of about 823,606 (243)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Assessing Physicians' Knowledge, Attitudes, and Practices in Occupational Disease Diagnosis and History Taking. [PDF]

Int J Environ Res Public Health
Al-Busaidi S, Al Maqrashi N, Alwahshi S, Alsaidi Y.   +3 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Tips of family history taking in diagnosing Alport syndrome: a report of six cases. [PDF]

CEN Case Rep
Mori T.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Corrigendum: Neurological history both twinned and queried by generative artificial intelligence

Frontiers in Medicine
Jung-Hyun Lee, Jung-Hyun Lee, Jung-Hyun Lee, Eunhee Choi, Sergio L. Angulo, Sergio L. Angulo, Robert A. McDougal, Robert A. McDougal, Robert A. McDougal, Robert A. McDougal, William W. Lytton, William W. Lytton, William W. Lytton   +12 more
doaj   +1 more source

Community pharmacists' history taking practice in responding to acute uncomplicated cystitis: A simulated patient study from Sudan. [PDF]

PLoS One
Hamadouk RM, Albashair ED, Alshareif EM, Saeed AA, Yousef BA.   +4 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Clinical paediatrics, history taking, and case discussion

Journal of Indian Association of Pediatric Surgeons, 2017
Parthasarathi Bhattacharyya
doaj   +1 more source

Development of a history-taking form for mesothelioma patients at risk of exposure to asbestos. [PDF]

Public Health Action
Singh R, Kumar R, Nagar M, Kaipilyawar SB, Anderson HA, Jadhav AV, Patel T, Drischoll TR, Prriya E, Yadav SR, Bishnoi S, Singh N, Kaur K, Jakhetiya A, van Zandwijk N, Kumari S, Khosla D, Rajan S, Verma AK, Bhatt A, Sharma A, Sinha DK, Kapoor A, Gill R, Dada R, Kishore J, Frank AL.   +26 more
europepmc   +1 more source