Results 171 to 180 of about 10,473,577 (342)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Jesus: His Life—Perspectives of Joseph and John the Baptist (Pt. 1)

open access: yes, 2019
As the calendar approaches Easter, made-for-television movies and documentaries appear on the History Channel, CNN, the National Geographic Channel, and other venues; and, why not?
Anderson, Paul N.
core  

Computerized history-taking as a tool to manage dyslipidemia

open access: yesVascular Health and Risk Management, 2010
David Zakim1, Christine Fritz2, Niko Braun1,3, Peter Fritz1, M Dominik Alscher1,31Institute for Digital Medicine, Stuttgart, Germany; 2University of Ulm, Ulm, Germany; 3Robert Bosch Krankenhaus, Stuttgart, GermanyBackground: Validated guidelines to ...
David Zakim   +3 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

User experience of self‐reported computerized medical history taking for acute chest pain: The Clinical Expert Operating System Chest Pain Danderyd Study [PDF]

open access: gold, 2022
Kay Sundberg   +8 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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