Results 61 to 70 of about 2,133,966 (310)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

FUNCTION IN BIOLOGY: ETIOLOGICAL AND ORGANIZATIONAL PERSPECTIVES

Acta Biológica Colombiana, 2009
. In this paper, we argue for a taxonomy of approaches to function based on different epistemological perspectives assumed with regard to the treatment of this central concept in the life sciences.
Charbel Niño El-Hani, Nei Freitas Freitas Nunes Neto   +1 more
doaj  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

The influence of transmedia and extra-academic narratives on the formation of the historical culture of high school students

Frontiers in Education
This paper concerns with the importance of traditional and extra-academic sources of knowledge in the configuration of historical culture of Spanish adolescents.
Pablo Muñoz-Muñoz, Jorge Ortuno-Molina, Sebastian Molina-Puche   +2 more
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Representaciones y perspectivas prácticas sobre las finalidades de la enseñanza de la historia en los/las estudiantes del profesorado

Clio y Asociados, 2017
In this article we address the representations and perspectives practices that underlie student teacher (National University of Comahue) on the aims of teaching history.
Miguel Angel Jara, Víctor Salto, Fabiana Értola   +2 more
doaj   +1 more source

The History Major and Undergraduate Liberal Education [PDF]

, 2008
Argues that the study of history integrates disciplinary knowledge, methods, and principles into a broad education and civic engagement. Recommends that departments set goals for student outcomes, diversify course requirements, and emphasize ...
James Grossman, Stanley N. Katz
core  

The Petrie Museum of Egyptian Archaeology: Characters and Collections [PDF]

, 2015
The Petrie Museum of Egyptian Archaeology first opened its doors in 1915, and since then has attracted visitors from all over the world as well as providing valuable teaching resources. Named after its founder, the pioneering archaeologist Flinders Petrie,
Stevenson, AE
core   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

A Independência e uma cultura de história no Brasil

Almanack
Resumo O objetivo deste artigo é propor uma análise preliminar de atitudes e valores que os brasileiros da atualidade nutrem diante de um fato histórico específico - a Independência do Brasil - bem como refletir acerca das relações de tais valores e ...
João Paulo Pimenta, César Augusto Atti, Sheila Virgínia Castro, Nadiesda Dimambro, Beatriz Duarte Lanna, Marina Pupo, Luís Otávio Vieira   +6 more
doaj   +1 more source