Results 131 to 140 of about 2,271,562 (311)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Forecasting annual CO2 emissions in Vietnam using ARIMA; Holt-Winters exponential smoothing models [PDF]

open access: yesE3S Web of Conferences
This study uses time series modeling approaches, notably Autoregressive Integrated Moving Average (ARIMA) and Holt-Winters models, to forecast Vietnam’s annual CO2 emissions.
Ta Thi Huong   +4 more
doaj   +1 more source

The Influence of Surface Detail on Object Identification in Alzheimer's Patients and Healthy Participants [PDF]

open access: yes, 2009
Image format (Laws, Adlington, Gale, Moreno-Martínez, & Sartori, 2007), ceiling effects in controls (Fung et al., 2001; Laws et al., 2005; Moreno-Martínez, & Laws, 2007; 2008), and nuisance variables (Funnell & De Mornay Davis, 1996; Funnell & Sheridan ...
Adlington, R.L.
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding

open access: yesNature Reviews Chemistry, 2021
S. Ackloo   +38 more
semanticscholar   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Modeling and Experimental Validation for Hammer-Driven Type Penetrators under Horizontal Condition

open access: yesShock and Vibration, 2016
This paper proposed a method used to analyze the motion of hammer-driven type penetrators and built a testbed for validating the result of structure optimization of the penetrator in deep space exploration.
Yi Shen   +4 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Hastanelerde Hasta Yakınları Tarafından Belirlenen İletişim Engellerinin Çeşitli Değişkenlere Göre İncelenmesi

open access: yesİletişim Kuram ve Araştırma Dergisi, 2018
Bu çalışma, hastanede hasta yakınları tarafından belirlenen iletişim engellerini çeşitli değişkenlere göre incelenmesini amaçlamaktadır. Araştırma, Türkiye’nin Güneydoğusunda bulunan Gaziantep Üniversitesi Şahinbey Araştırma ve Uygulama Hastanesi’nde ...
Bayram Oğuz Aydın, Emine Şahin
doaj  

Documenting Poverty, Economic Distress and Challenge in North Carolina [PDF]

open access: yes, 2010
Analyzes trends in economic distress, progress, and opportunity and recommends place-based, multifaceted economic strategies with a focus on chronically poor rural counties; distressed parts of urban centers; and communities hit hard by the ...

core  

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