Results 151 to 160 of about 707,804 (298)

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source

HIV-1 transcription dominates over host gene activity at the HIV-1 integration site. [PDF]

mBio
Weissman S, Yeh Y-HJ, Viazmenski M, Kim R, Collora JA, Steinhauser S, Ho Y-C.   +6 more
europepmc   +1 more source

Glucose-Fueled Histone Modifications Drive HIV-1 Latency Reversal at Hypoxia [PDF]

H. H. Taylor, Deanna C. Clemmer, Adebola A. Owolabi, AbdulKareem A. AlShaheeb, Elyse K. McMahon, Anna Tangiyan, Lauren Clark, Glenn E. Simmons, Alberto Bosque, Melanie R. McReynolds, Harry E. Taylor   +10 more
openalex   +1 more source

Antibodyomics: bioinformatics technologies for understanding B‐cell immunity to HIV‐1 [PDF]

, 2017
Peter D. Kwong, Gwo‐Yu Chuang, Brandon J. DeKosky, Tatyana Gindin, Ivelin S. Georgiev, Thomas Lemmin, Chaim A. Schramm, Zizhang Sheng, Cinque Soto, An‐Suei Yang, John R. Mascola, Lawrence Shapiro   +11 more
openalex   +1 more source

Navigating an STI diagnosis: The role of social support, intergenerational learning, and transformative growth among Black women

American Journal of Community Psychology, EarlyView.
Abstract Black women face a myriad of challenges that heighten their susceptibility to sexually transmitted infections (STIs), resulting in a disproportionate impact of STIs among this population. Yet, there is a lack of research that explores how women navigate these diagnoses with resilience.
Jaleah D. Rutledge, Jasmine Abrams, Ijeoma Opara, Robin Lin Miller   +3 more
wiley   +1 more source

Transforming RNA Degradation into Accurate RNA Detection: RNase I–Assisted Rolling Circle Amplification for Clinical Samples

Angewandte Chemie, EarlyView.
Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai, Cheng‐Yu Lee, Zijie Zhang, Jimmy Gu, John D. Brennan, Yingfu Li   +5 more
wiley   +2 more sources

The intersection of health inequalities and COVID‐19: Evidence from National Health Insurance Big Data in South Korea

American Journal of Community Psychology, EarlyView.
Abstract Health inequalities persist along lines of income and wealth, shaped by unequal access to healthcare, differences in health behaviors, and pre‐existing chronic conditions. The COVID‐19 pandemic further put families in Korea under health strain and worsened their health outcomes.
Jaehyun Nam, Sarah Jiyoon Kwon, Wonik Lee, Eunji Kim   +3 more
wiley   +1 more source

Human immunodeficiency virus (HIV) type 1 genetic diversity in HIV positive individuals on antiretroviral therapy in a cross sectional study conducted in Teso, Western Kenya

, 2021
Maureen Adhiambo, Olipher Makwaga, Ferdinard Adungo, Humphrey Kimani, David H. Mulama, Jackson C. Korir, Matilu Mwau   +6 more
openalex   +1 more source

HIV-1-specific CD8⁺ T cells with different abilities to recognize HIV-1-infected cells in HIV-1-exposed seronegative individuals. [PDF]

PNAS Nexus
Nguyen HT, Chikata T, Kuse N, Zhang Y, Pham DTN, Do NT, Nguyen TC, Lung NB, Bui HTM, Gatanaga H, Van Tran G, Nguyen BT, Van Nguyen D, Giang LM, Oka S, Takiguchi M.   +15 more
europepmc   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source