Results 281 to 290 of about 658,368 (320)

Optimization of a lentivirus-mediated gene therapy targeting HIV-1 RNA to eliminate HIV-1-infected cells. [PDF]

Mol Ther Nucleic Acids
Buckingham AB, Ho S, Knops-Mckim F, Ingemarsdotter CK, Lever AML.   +4 more
europepmc   +1 more source

OMIP‐114: A 36‐Color Spectral Flow Cytometry Panel for Detailed Analysis of T Cell Activation and Regulation in Small Human Blood Volumes

Cytometry Part A, EarlyView.
ABSTRACT This 36‐color flow cytometry panel is designed to characterize multiple lymphocyte compartments, with a focus on T cells, their memory subpopulations, and immune checkpoints in human whole blood samples. In clinical settings, the amount of blood available from patients for scientific research is often limited.
Marie‐Theres Thieme‐Ehlert, Thomas Jacobs, Johannes Brandi, Maria Sophia Mackroth   +3 more
wiley   +1 more source

Structural basis for HIV-1 capsid adaption to rescue IP6-packaging deficiency

Zhu Y, Kleinpeter AB, Rey JS, Shen J, Shen Y, Xu J, Hardenbrook N, Chen L, Lucic A, Perilla JR, Freed EO, Zhang P.   +11 more
europepmc   +1 more source

Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity. [PDF]

PLoS Pathog
Foulkes C, Friedrich N, Ivan B, Stiegeler E, Magnus C, Schmidt D, Karakus U, Weber J, Günthard HF, Pasin C, Rusert P, Trkola A.   +11 more
europepmc   +1 more source

Automated analysis of flow cytometry data with minimal training files: Research evaluation of an elastic image registration algorithm for TBNK, stem cell enumeration, and lymphoid screening tube assays

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Automated analysis of flow cytometry data can improve objectivity and reduce analysis time but has generally required work by software and algorithm experts. Here, we investigated the performance of BD ElastiGate™ Software (hereafter ElastiGate), which allows users to automate gating by selecting gated training files, then uses elastic image ...
Allison Irvine, Suhail Tahir, Vishnu Tripathi, Farzad Oreizy, Moen Sen, Anthony Giuliano, Anna Lin, Angela Chen, Chih‐Hung Lai, Imelda Omana‐Zapata, Yang Zeng, Paresh Jain, Scott J. Bornheimer   +12 more
wiley   +1 more source

Editorial Expression of Concern to: Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein. [PDF]

Cell Death Dis
Abbas W, Khan KA, Kumar A, Tripathy MK, Dichamp I, Keita M, Mahlknecht U, Rohr O, Herbein G.   +8 more
europepmc   +1 more source

Differentiating reactive and neoplastic gamma‐delta (γδ) T‐cell expansions in the peripheral blood and bone marrow

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract The clinical and immunophenotypic attributes of reactive γδ T‐cell expansions are less well characterized than their malignant counterparts, which can pose diagnostic challenges. This study aims to investigate the characteristics and long‐term clinical outcomes of reactive γδ T‐cell expansions.
Hamza Tariq, Zubair Ilyas, Lucy Fu, Yijie Liu, Qing Ching Chen, Kristy Wolniak, Yi‐Hua Chen   +6 more
wiley   +1 more source

Analysis of HIV-1 recent infections and hotspot areas in a bordering area in Yunnan Province, China. [PDF]

BMC Public Health
Zhang X, Dong L, Zhou T, Chen H, Han Y, Jin X, Dai J, Yang M, Zeng Z, Sun P, Ma Y, Shi Y, Chen M, Jia M.   +13 more
europepmc   +1 more source

Correction: Functional and structural segregation of overlapping helices in HIV-1.

Elife
Safari M, Jayaraman B, Zommer H, Yang S, Smith C, Fernandes JD, Frankel AD.   +6 more
europepmc   +1 more source

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration. [PDF]

mBio
Ingram Z, Kline C, Hughson AK, Singh PK, Fischer HL, Radhakrishnan R, Sowd GA, Dos Santos NFB, Ganser-Pornillos BK, Watkins SC, Kane M, Engelman AN, Ambrose Z.   +12 more
europepmc   +1 more source