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Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease.
Annual Review of Immunology, 1999In addition to CD4, the human immunodeficiency virus (HIV) requires a coreceptor for entry into target cells. The chemokine receptors CXCR4 and CCR5, members of the G protein-coupled receptor superfamily, have been identified as the principal coreceptors
E. Berger, P. Murphy, J. Farber
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The Lancet, 2007
Taiwan is entering a new and dangerous phase of its HIV-1/AIDS epidemic. By the end of 2006 13 702 individuals (including 599 foreigners) had been reported as infected with HIV-1 to the Centers for Disease Control of Taiwan. In 2003 HIV-1 rates in first-time blood donors military conscripts and pregnant women were measured at 5.2 57.0 and 12.0 per 100 ...
Yi Ming Arthur Chen, Steve Hsu Sung Kuo
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Taiwan is entering a new and dangerous phase of its HIV-1/AIDS epidemic. By the end of 2006 13 702 individuals (including 599 foreigners) had been reported as infected with HIV-1 to the Centers for Disease Control of Taiwan. In 2003 HIV-1 rates in first-time blood donors military conscripts and pregnant women were measured at 5.2 57.0 and 12.0 per 100 ...
Yi Ming Arthur Chen, Steve Hsu Sung Kuo
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Psychoneuroimmunology and HIV-1.
Journal of Consulting and Clinical Psychology, 1990Recent psychoneuroimmunologic findings have suggested that it may be useful to evaluate the influence of behavioral factors on immune functioning and disease progression among human immunodeficiency virus-Type 1 (HIV-1) infected individuals. Behavioral interventions with immunomodulatory capabilities may help restore competence and thereby arrest HIV-1
Antoni, M H +5 more
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Current Opinion in HIV and AIDS, 2011
Macrophages play an important role in HIV-1 pathogenesis and contribute to the establishment of the viral reservoir responsible for continuous virus production. This review will discuss new insights into HIV-1 infection in macrophages and the effect of infection on immune function and pathology.New cellular factors interacting with various steps of the
Jörg Hamann +3 more
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Macrophages play an important role in HIV-1 pathogenesis and contribute to the establishment of the viral reservoir responsible for continuous virus production. This review will discuss new insights into HIV-1 infection in macrophages and the effect of infection on immune function and pathology.New cellular factors interacting with various steps of the
Jörg Hamann +3 more
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HIV-1 and the etiology of AIDS [PDF]
International Journal of Gynecology & Obstetrics, 1993 The belief that HIV-1 infection causes AIDs has been questioned, and the suggestion made that to know the correct cause of AIDS the incidence of disease in patients with and without risk behaviours and with and without antibody to HIV-1 must be known. We describe findings in such a cohort.
M.T. Schechter +8 more
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Mixed Cryoglobulinemia in HIV-1 Infection: The Role of HIV-1
Annals of Internal Medicine, 1999Cryoglobulins are associated with chronic infections.To investigate the prevalence of mixed cryoglobulinemia in patients with HIV-1 infection, the clinical spectrum of cryoglobulinemia in these patients, and the possible role of HIV-1 in cryoglobulin formation.Prospective cohort study.Laiko Hospital, Athens, Greece.89 patients with HIV-1 infection ...
Haralampos M. Moutsopoulos +3 more
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Enhanced infectivity of HIV-1 by X4 HIV-1 coinfection
Biochemical and Biophysical Research Communications, 2003Two strains of human immunodeficiency virus type 1 (HIV-1) expressing different reporters, human placental alkaline phosphatase (PLAP) and murine heat stable antigen (HSA, CD24), were used for dual infection. Flow cytometric analysis enabled us to distinguish cells not only infected with individual reporter virus but also superinfected with both ...
Keisuke Yusa +2 more
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HIV-1–specific CTLs effectively suppress replication of HIV-1 in HIV-1–infected macrophages
Blood, 2007AbstractBoth CD4+ T cells and macrophages are major reservoirs of HIV-1. Previous study showed that HIV-1–specific cytolytic T lymphocytes (CTLs) hardly recognize HIV-1–infected CD4+ T cells because of Nef-mediated HLA class I down-regulation, suggesting that HIV-1 escapes from HIV-1–specific CTLs and continues to replicate in HIV-1–infected donors. On
Masafumi Takiguchi, Mamoru Fujiwara
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, 2013 The term “virus maturation” in general refers to alterations of the architecture of a virus that occur after the particle with all its constituents has been formed. In the case of HIV-1 and other retroviruses, maturation involves cleavage of the main structural polyprotein, Gag, by the virusencoded protease once the immature virion is released from the
Barbara Müller, Hans-Georg Kräusslich
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Nature Medicine, 2003
Despite considerable advances in HIV science in the past 20 years, the reason why HIV-1 infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains elusive. A deeper understanding of the interplay between HIV-1 and its host and why simian immunodeficiency virus (SIV) is nonpathogenic in some natural hosts may provide a ...
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Despite considerable advances in HIV science in the past 20 years, the reason why HIV-1 infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains elusive. A deeper understanding of the interplay between HIV-1 and its host and why simian immunodeficiency virus (SIV) is nonpathogenic in some natural hosts may provide a ...
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