Results 281 to 290 of about 141,192 (322)

Molecular mechanisms of HIV-1 genetic diversity

Molecular Biology, 2017
High genetic diversity of HIV-1 is the main factor behind the fact that HIV infection is widespread and difficult to treat. Although a limited number (or only one) of virus particles enters the blood upon infection, the particles are replicated in infected cells and rapidly produce new genetic variants that are resistant to the host immune system and ...
D V, Sosin, N A, Tchurikov
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High HIV-1 genetic diversity in Cuba

AIDS, 2002
HIV-1 subtype B is largely predominant in the Caribbean, although other subtypes have been recently identified in Cuba.To examine HIV-1 genetic diversity in Cuba.The study enrolled 105 HIV-1-infected individuals, 93 of whom had acquired the infection in Cuba.
María Teresa, Cuevas, Ignacio, Ruibal, María Luisa, Villahermosa, Héctor, Díaz, Elena, Delgado, Elena Vázquez-de, Parga, Lucía, Pérez-Alvarez, Madelín Blanco, de Armas, Laureano, Cuevas, Leandro, Medrano, Enrique, Noa, Saladin, Osmanov, Rafael, Nájera, Michael M, Thomson   +13 more
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Emerging genetic diversity of HIV-1 in South America

AIDS, 2000
Genotype determination and risk group analysis of HIV-1 infected individuals in selected regions of South America.Cross-sectional convenience sampling of HIV-1-positive individuals in Peru, Ecuador, Uruguay and Paraguay from March, 1994 through September, 1998.HIV-1-positive subjects were identified through the national AIDS surveillance program in ...
K L, Russell, C, Carcamo, D M, Watts, J, Sanchez, E, Gotuzzo, A, Euler, J C, Blanco, A, Galeano, A, Alava, J I, Mullins, K K, Holmes, J K, Carr   +11 more
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EVOLUTION OF INTRAHOST HIV-1 GENETIC DIVERSITY DURING CHRONIC INFECTION

Evolution, 2006
HIV-1 is one of the fastest evolving entities known. Given that census population sizes of HIV-1 within individuals are much greater than the inverse mutation rate, every possible single point mutation in the viral genome occurs each generation. This enormous capability to generate genetic variation allows for escape from immune surveillance and ...
Daniel, Shriner, Yi, Liu, David C, Nickle, James I, Mullins   +3 more
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Sex and the genetic diversity of HIV-1

Nature Medicine, 2000
The genetic variability of HIV-1 is an important aspect of its pathogenesis, even though studies in men have demonstrated that the viral population is usually homogeneous during the first months of infection. Now, a large study comparing men and women shows that even before an antibody response is detectable, the viral population differs between the ...
Stuart C. Ray, Thomas C. Quinn
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The Genetic Diversity of HIV-1 Quasispecies Within Primary Infected Individuals

AIDS Research and Human Retroviruses, 2020
HIV has remarkable genetic diversity among populations. The diversity has critical impacts on transmission, immune escape, pathogenesis, and clinical management. HIV-1 diversity originates from frequent mutation and recombination during reverse transcription.
Yongjian, Liu, Lei, Jia, Bin, Su, Hanping, Li, Zhen, Li, Jingwan, Han, Yu, Zhang, Tong, Zhang, Tianyi, Li, Hao, Wu, Jingyun, Li, Lin, Li   +11 more
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HIV-1 genetic diversity.

AIDS (London, England), 1997
HIV-1 evolves by rapid mutation and by recombination, both processes actively contributing to its genetic diversity. Most of the multiple genetic subtypes and intersubtype recombinations of HIV-1 that comprise the global pandemic have not been characterized by full genome sequencing.DNA from primary virus cultures on donor peripheral blood mononuclear ...
F E, McCutchan, M O, Salminen, J K, Carr, D S, Burke   +3 more
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High genetic diversity of HIV-1 viruses in Macao, China

Journal of Infection, 2010
To investigate the molecular epidemiology of recently diagnosed HIV-1 infection in Macao for better understanding the epidemiology in this Chinese city, in context of its relationship with other countries in Asia and the rest of the world.Serum samples of HIV positive cases reported between 2005 and 2007 were collected from the Macao Public Health ...
Yi, Tan, Desmond, Chan, Denise, Chan, Peng Kei, Ip, Chong, Lam, Nga Yin, Fong, Stephen Kwok-Wing, Tsui, Shui Shan, Lee   +7 more
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Detection of diverse HIV-1 genetic subtypes in the USA

The Lancet, 1995
Of the nine genetic subtypes of HIV-1 that exist world wide, subtype B predominates in North America and Europe. Thus, most knowledge about HIV-1 and most vaccine development efforts are based on subtype B viruses. We document here the detection of HIV-1 subtypes A, D, and E in five US servicemen who acquired these non-subtype-B infections during ...
S K, Brodine, J R, Mascola, P J, Weiss, S I, Ito, K R, Porter, A W, Artenstein, F C, Garland, F E, McCutchan, D S, Burke   +8 more
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HIV‐1 genetic diversity and transmitted drug resistance among newly diagnosed HIV‐1 individuals in Jiangmen, China

Journal of Medical Virology, 2020
AbstractJiangmen is one of the Guangdong‐Hong Kong‐Macao Greater Bay Areas with frequent commercial intercourse, which is responsible for human immunodeficiency virus type 1 (HIV‐1) rapid circulation and genetic evolution for recent years. As a novel HIV‐1 second‐generation recombinant was previously reported in Jiangmen but the systematic molecular ...
Xin Guan, Min Han, Zhiju Li, Lihua Wang, Donghe Zhang, Yanan Zhu, Guifang Hu   +6 more
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