Results 291 to 300 of about 141,192 (322)

Genetic Diversity and Drug Resistance of HIV-1 CRF55_01B in Guangdong, China

Current HIV Research, 2020
Background: HIV-1 CRF55_01B was first reported in 2013. At present, no report is available regarding this new clade’s polymorphisms in its functionally critical regions protease and reverse transcriptase. Objective: To identify the diversity difference in protease and reverse transcriptase between CRF55_01B and its parental clades CRF01_AE and ...
Guolong Yu, Yan Li, Xuhe Huang, Pingping Zhou, Jin Yan, Xinge Yan, Xiaobing Fu, Yang Fang, Jun Liu, Jie Li, Xiang He, Peng Lin   +11 more
openaire   +2 more sources

Nucleotide Sequence of a Ugandan HIV-1 Provirus Reveals Genetic Diversity from Other HIV-1 Isolates

AIDS Research and Human Retroviruses, 1990
A Ugandan isolate of human immunodeficiency virus type 1 (HIV-1), designated U455, was adapted to growth in U937 cells, the provirus cloned into the lambda L47.1 vector, and its DNA sequence determined. The sequences of some of the U455 genes showed a marked divergence from those of North American and other African isolates.
J D, Oram, R G, Downing, M, Roff, J C, Clegg, D, Serwadda, J W, Carswell   +5 more
openaire   +2 more sources

High Genetic Diversity of HIV-1 Strains in Chad, West Central Africa

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2003
The genetic diversity of HIV-1 strains in Chad was documented with a total of 107 samples from patients attending the general hospital in N'Djamena, the capital city of Chad. The genetic subtypes were identified in the V3-V5 env and p24 gag regions by sequence and phylogenetic tree analyses.
Nicole, Vidal, Donato, Koyalta, Vincent, Richard, Catherine, Lechiche, Thomas, Ndinaromtan, Abakar, Djimasngar, Eric, Delaporte, Martine, Peeters   +7 more
openaire   +2 more sources

Surveillance of HIV‐1 genetic subtypesand diversity in the US blood supply

Transfusion, 2000
BACKGROUND: Recent reports of variant (non‐subtype B) HIV infections in US populations have raised concerns about the sensitivity of subtype B virus‐based donor screening and diagnostic assays. This study was designed to determine the prevalence and genetic diversity of HIV subtypes in US blood donors over the last two decades.STUDY DESIGN AND METHODS:
C F, de Oliveira, R S, Diaz, D M, Machado, M T, Sullivan, T, Finlayson, M, Gwinn, E M, Lackritz, A E, Williams, D, Kessler, E A, Operskalski, J W, Mosley, M P, Busch   +11 more
openaire   +2 more sources

HIV-1 drug resistance and genetic diversity in people with HIV-1 in Cape Verde

AIDS
Objectives: To characterize the genetic diversity and drug resistance profiles of people with HIV-1 failing ART in Cape Verde (CV). Design: Cross-sectional study conducted between January 2019 and December 2021 in 24 health centres on the islands of Santiago and São Vicente.
Paloma, Gonçalves, Jorge, Barreto, Menilita, Santos, Silvania, Leal, José, Marcelino, Ana, Abecasis, Claudia, Palladino, Nuno, Taveira   +7 more
openaire   +2 more sources

Molecular screening shows extensive HIV-1 genetic diversity in Central West Brazil

Journal of Clinical Virology, 2007
Information is limited about HIV-1 subtypes circulating in less populated Brazilian areas where the AIDS epidemic is expanding, such as in the Central West region.To describe HIV-1 subtypes in patients from the States of Goias, Mato Grosso do Sul and Mato Grosso in Central West Brazil.Heteroduplex mobility analysis of nested-PCR products from env ...
Mariane M A, Stefani, Gisner A S, Pereira, Janaina A B, Lins, Keila C, Alcantara, Alexsander A, Silveira, Angela A, Viegas, Nadia C, Maya, Aparecida Hg, Mussi   +7 more
openaire   +2 more sources

Genetic Diversity of HIV-1 GenevifAmong Treatment-Naive Brazilians

AIDS Research and Human Retroviruses, 2017
HIV-1 has the Vif protein, which binds to human antiviral proteins APOBEC3 to form complexes to be degraded by cellular proteolysis. To further explore HIV-1 diversity at the population level, we analyzed blood samples from 317 treatment-naive patients in Brazil.
Villanoval, Fabiola, Barreiros, Marta, Janini, Luiz Mario UNIFESP, Diaz, Ricardo Sobhie UNIFESP, Leal, Elcio   +4 more
openaire   +3 more sources

High HPV genetic diversity in women infected with HIV-1 in Brazil

Archives of Virology, 2006
The present study on genetic diversity of human papillomaviruses in women infected by HIV in Brazil describes the frequency, the genotypes, and five new variants of HPV. One hundred fifty cervical smears of HIV-positive women were subjected to cytological examination, and the DNA samples obtained were assayed by MY09/MY11 amplification, followed by ...
D M, Cerqueira, D, de S Moraes, G N L, Camara, F A, Amaral, C N R, Oyama, M Q C, dos Santos, C R F, Martins   +6 more
openaire   +2 more sources

HIV-1 Genetic Diversity and Its Biological Significance

2009
Differences between HIV-1 genetic clades on pathogenicity, transmissibility, and other biological features often have been difficult to prove, due to multiple factors, including large intrasubtype diversity, frequent recombination, and methodological issues.
openaire   +1 more source

Diverse HIV-1 genetic subtypes in UK

The Lancet, 1996
J P, Clewley, C, Arnold, K L, Barlow, P R, Grant, J V, Parry   +4 more
openaire   +2 more sources