Results 1 to 10 of about 653,464 (118)

The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture [PDF]

Journal of Virus Eradication, 2023
A better understanding of HIV-1 latency is a research priority in HIV cure research. Conversely, little is known about the latency characteristics of HIV-2, the closely related human lentivirus.
Anne Bruggemans, Gerlinde Vansant, Paulien Van de Velde, Zeger Debyser   +3 more
doaj   +2 more sources

Macrophage-Derived Factors with the Potential to Contribute to Pathogenicity of HIV-1 and HIV-2: Role of CCL-2/MCP-1 [PDF]

Viruses, 2023
Human immunodeficiency virus type 2 (HIV-2) is known to be less pathogenic than HIV-1. However, the mechanism(s) underlying the decreased HIV-2 pathogenicity is not fully understood. Herein, we report that β-chemokine CCL2 expression was increased in HIV-
Chunling Gao, Weiming Ouyang, Joseph Kutza, Tobias A. Grimm, Karen Fields, Carla S. R. Lankford, Franziska Schwartzkopff, Mark Paciga, Tzanko Stantchev, Linda Tiffany, Klaus Strebel, Kathleen A. Clouse   +11 more
doaj   +2 more sources

Seroprevalence of HIV-1 and HIV-2 Infections at an ICTC in A Tertiary Care Hospital in Pondicherry

Journal of Pure and Applied Microbiology, 2022
Purpose of the study: To estimate the prevalence of HIV 1 and HIV 2 infection in patients attending the tertiary care setup. Routine screening for HIV infection of 10000 samples were carried out between July 2017-June 2018.
Y. Valentina, Johan Pandian
doaj   +1 more source

Implementation of point-of-care testing and prevalence of cryptococcal antigenaemia among patients with advanced HIV disease in Mumbai, India

BMJ Open, 2023
Objectives To describe the implementation of screening for cryptococcal antigenaemia by point-of-care (POC) serum cryptococcal antigen (CrAg) lateral flow assay, measure the prevalence and factors associated with serum cryptococcal antigenaemia in the ...
Amit Harshana, Raman Mahajan, Reshu Agarwal, Shrikala Acharya, Amol Palkar, Ramesh Reddy Allam, Vijay Kumar Karanjkar, Dhirubhai Rathod, Prashant Deshpande, Shashikant Todmal, Sagar Koli, Sachin Dhande, Jayesh Dale, Vijay V Yeldandi, Sunita Upadhyaya, Melissa Nyendak   +15 more
doaj   +1 more source

Country adherence to WHO recommendations to improve the quality of HIV diagnosis: a global policy review

BMJ Global Health, 2020
Introduction Ensuring a correct and timely HIV diagnosis is critical. WHO publishes guidelines on HIV testing strategies that maximise the likelihood of correctly determining one’s HIV status.
Cheryl Johnson, Virginia A Fonner, Anita Sands, Carmen Figueroa, Rachel Baggaley, Caitlin Quinn, Muhammad S Jamil   +6 more
doaj   +1 more source

Adolescents and age of consent to HIV testing: an updated review of national policies in sub-Saharan Africa

BMJ Open, 2021
Objectives In sub-Saharan Africa (SSA) where HIV burden is highest, access to testing, a key entry point for prevention and treatment, remains low for adolescents (aged 10–19). Access may be hampered by policies requiring parental consent for adolescents
Cheryl Johnson, Wole Ameyan, Rachel Baggaley, Caitlin Quinn, Muhammad S Jamil, Keith Sabin, Magdalena Barr-DiChiara, Mandikudza Tembo, Lisa Harrison, Bhavin Jani   +9 more
doaj   +1 more source

Urinary Neopterin Indicates Early Infection and Disease Progression: Model Studies with Simian and Human Immunodeficiency Viruses in Macaques

Pteridines, 2002
The value of urinary neopterin as a predictive marker for disease progression in SIV- and HIV-2-infected rhesus (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis) was assessed by comparing pre- with postinfection data. Before infection stable
Stahl-Hennig Christiane, Fendrich Claudia, Lüke Wolfgang, Widner Bernhard, Hunsmann Gerhard, Fuchs Dietmar   +5 more
doaj   +1 more source

High prevalence and excess mortality of late presenters among HIV-1, HIV-2 and HIV-1/2 dually infected patients in Guinea-Bissau - a cohort study from West Africa

The Pan African Medical Journal, 2016
INTRODUCTION: HIV infected individuals with late presentation (LP) and advanced disease (AD) have been associated with higher mortality, higher cost of medical management, impaired CD4 cell count increment and potentially ongoing risk of HIV transmission.
Bo Langhoff Henge, Sanne Jespersen, Johanna Aunsborg, Delfim Vicente Mendes, Candida Medina, David da Silva Te, Alex Lund Laursen, Christian Erikstrup, Christian Wejse, The Bissau HIV cohort study group   +9 more
doaj   +1 more source

Incidence of diabetes mellitus among people living with and without HIV in British Columbia, Canada between 2001 and 2013: a longitudinal population-based cohort study

BMJ Open, 2021
Introduction People living with HIV (PLHIV) are increasingly at risk of age-related comorbidities such as diabetes mellitus (DM). While DM is associated with elevated mortality and morbidity, understanding of DM among PLHIV is limited.
Kate Salters, Taylor McLinden, Monica Ye, Jenny Li, Paul Sereda, Viviane Lima, Robert Hogg, Silvia Guillemi, Ni Gusti Ayu Nanditha, Andreea Bratu, Katherine Kooij, Jason Trigg   +11 more
doaj   +1 more source

HIV-1/2 differentiation in a South African public laboratory

Southern African Journal of HIV Medicine, 2021
Background: The human immunodeficiency virus type-2 (HIV-2) prevalence in South Africa (SA) is unknown, however, sporadic cases have been reported.
Rendani T. Mafuyeka, Lynne M. Webber, Piet Becker, Simnikiwe H. Mayaphi   +3 more
doaj   +1 more source