Results 161 to 170 of about 89,605 (248)

O4 Spatial distribution of HIV in antiretroviral-treated humanised mice

open access: yesJournal of Virus Eradication, 2016
Virginie Fievez   +7 more
doaj  

Inflammatory bowel disease type influences development of elevated liver enzymes

open access: yesJGH Open, Volume 6, Issue 12, Page 846-853, December 2022., 2022
We evaluated the incidence, predictors, and outcomes associated with elevated liver enzymes (ELE) in a diverse and vulnerable inflammatory bowel disease cohort. In multivariate Cox regression, ulcerative colitis (vs Crohn's disease) had a 34% lower risk of developing new ELE during follow‐up (hazard ratio 0.66, 95% confidence interval: 0.46–0.95, P = 0.
Yao‐Wen Cheng   +4 more
wiley   +1 more source

Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co‐infected patients in Ukraine

open access: yesJGH Open, Volume 6, Issue 12, Page 894-903, December 2022., 2022
We assessed treatment and cost outcomes for integrated HIV and viral hepatitis testing with ledipasvir/sofosbuvir ± weight‐based ribavirin for 12 weeks in Kyiv, Ukraine. Overall, a sustained virological response (SVR) was achieved in 831 of 868 patients (95.7%).
Sergie Antoniak   +24 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Obliterative portal venopathy: A neglected and probably misdiagnosed disease with peculiar etiology in South America

open access: yesJGH Open, Volume 6, Issue 12, Page 904-909, December 2022., 2022
Classically described in the group of non‐cirrhotic portal hypertension, obliterative portal venopathy (OPV) causes are still unknown. Our aim is to describe the characteristics of 43 OPV patients and potential risk factors. Clinically significant portal hypertension was found in 28% of cases. The most frequent indication for liver biopsy was elevation
Vinícius Nunes   +7 more
wiley   +1 more source

HIV Infection and Renal Transplantation

open access: bronze, 1989
D. Novoa   +4 more
openalex   +1 more source

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

open access: yesExploration, EarlyView.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang   +15 more
wiley   +1 more source

Real‐world impact of a subsidy decision of sofosbuvir–velpatasvir for treatment of chronic hepatitis C on clinical practice and patient outcomes

open access: yesJGH Open, Volume 7, Issue 1, Page 48-54, January 2023., 2023
Sofosbuvir–velpatasvir was recommended for subsidy to treat chronic hepatitis C in Singapore in 2018, following which utilization trends and prescribing patterns were assessed using aggregated drug utilization data from public hospitals' dispensing systems and clinical data from the national electronic health record database.
Chee‐Kiat Tan   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy