Results 61 to 70 of about 639,534 (344)

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

HIV-Infected Patients

Biology of Blood and Marrow Transplantation, 2009
High-dose chemotherapy and autologous stem cell transplantation (SCT) or allogeneic SCT can lead to durable remissions in patients with hematologic malignancies. In the mid-1980s the first studies demonstrating the use of peripheral blood stem cells (PBSC) for autologous transplantation instead of bone marrow (BM) were performed.
openaire   +3 more sources

Terahertz Metamaterial Sensors: Design Theory, Optimization Approach, and Advancements in Biosensing Applications

Advanced Materials Technologies, EarlyView.
This review provides an in‐depth overview of the design principles and optimization strategies for terahertz (THz) metamaterials (MMs) sensors based on the dielectric perturbation theory. Various structures and methods are explored to enhance sensor performance, focusing on improving sensitivity and Q‐factor.
Lei Cao, Shanshan Jia, Fanqi Meng, Merle Richter, Yannik Loth, Anna Katharina Wigger, Chenglin Yang, Liuyang Zhang, Peter Haring Bolívar, Hartmut G. Roskos   +9 more
wiley   +1 more source

Fluctuations in Blood Marginal Zone B-Cell Frequencies May Reflect Migratory Patterns Associated with HIV-1 Disease Progression Status.

PLoS ONE, 2016
We have previously shown that overexpression of BLyS/BAFF was associated with increased relative frequencies of innate "precursor" marginal zone (MZ)-like B-cells in the blood of HIV-1-infected rapid and classic progressors.
Julie Gauvin, Josiane Chagnon-Choquet, Johanne Poudrier, Michel Roger, Montreal Primary HIV Infection and Slow Progressor Cohorts   +4 more
doaj   +1 more source

The enigma of HIV infection

Cell, 1995
The three reviews that follow this introduction reflect contemporary knowledge of human immunodeficiency virus (HIV) infection and disease induction. Let us take a step back and reflect on why this virus infection, against which 10% of the budget of the National Institutes of Health is deployed, remains so enigmatic. ; © 1995 by Cell Press.
openaire   +4 more sources

Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives

Advanced Sensor Research, EarlyView.
This review delves deeply into the various types of optical microfiber biosensors, grounded firmly in their fundamental principles, and underscores their indispensable roles in pushing forward biomedical advancements. It examines the latest advancements, challenges faced by these biosensors in practical applications, future directions, breakthroughs ...
Lili Liang, Fei Xie, Li Jin, Bowen Yang, Li‐Peng Sun, Bai‐Ou Guan   +5 more
wiley   +1 more source

The Human Penis Is a Genuine Immunological Effector Site

Frontiers in Immunology, 2017
The human penis is a main portal of entry for numerous pathogens, and vaccines able to control resulting infections locally are highly desirable. However, in contrast to the gastrointestinal or vaginal mucosa, the penile immune system and mechanisms ...
Alexis Sennepin, Alexis Sennepin, Alexis Sennepin, Fernando Real, Fernando Real, Fernando Real, Marine Duvivier, Marine Duvivier, Marine Duvivier, Yonatan Ganor, Yonatan Ganor, Yonatan Ganor, Sonia Henry, Sonia Henry, Sonia Henry, Diane Damotte, Marc Revol, Sonia Cristofari, Morgane Bomsel, Morgane Bomsel, Morgane Bomsel   +20 more
doaj   +1 more source

Use and awareness of and willingness to self-test for HIV: an analysis of cross-sectional population-based surveys in Malawi and Zimbabwe

BMC Public Health, 2020
Background Many southern African countries are nearing the global goal of diagnosing 90% of people with HIV by 2020. In 2016, 84 and 86% of people with HIV knew their status in Malawi and Zimbabwe, respectively.
Cheryl Johnson, Melissa Neuman, Peter MacPherson, Augustine Choko, Caitlin Quinn, Vincent J. Wong, Karin Hatzold, Rose Nyrienda, Getrude Ncube, Rachel Baggaley, Fern Terris-Prestholt, Elizabeth L. Corbett   +11 more
doaj   +1 more source

Willingness to receive the COVID-19 vaccine among HIV positive men who have sex with men in China: a cross-sectional study

BMC Public Health, 2023
Background People living with HIV(PLWH) are deemed more vulnerable to the SARS-CoV-2 infection than the uninfected population. Vaccination is an effective measure for COVID-19 control, yet, little knowledge exists about the willingness of men who have ...
Songjie Wu, Shanhui Zhu, Xumeng Yan, Yongshi Xu, Huifang Xu, Fang Yang, Zhigang Han, Yuzhou Gu, Yi Zhou, Zhengrong Yang, Huake Yang, Bo Shu, Weiming Tang, Ke Liang   +13 more
doaj   +1 more source

Latest Progress on Tuberculosis and HIV Co‐Infection: A Closer Look at People of Different Ages

Advanced Therapeutics, EarlyView.
Tackling the problem of tuberculosis (TB) and human immunodeficiency virus (HIV) co‐infection is a serious global health concern affecting people of all ages. This review presents the characteristics of both diseases, current treatment and diagnostic guidelines, associated problems, innovations in disease management, and overall effects on global ...
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
wiley   +1 more source