Results 101 to 110 of about 423,543 (284)

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

18F-FDG PET/CT Imaging of Talaromyces marneffei Infection with Bone Destruction in an HIV-Negative Patient: Case Report and Review

Infection and Drug Resistance
Wenting He,1 Senhui Wang,1 Xiaoqi Xiong,2 Wenli Dai1 1Department of Nuclear Medicine, The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei, 443003, People’s Republic of China; 2Department of Respiratory and ...
He W, Wang S, Xiong X, Dai W
doaj  

Impact of Human Immunodeficiency Virus Infection on the Outcome of Treatment and Survival of Tuberculosis Patients in Mwanza, Tanzania. [PDF]

, 1998
Little is known about the outcome of tuberculosis (TB) treatment and subsequent survival of human immunodeficiency virus (HIV) infected patients treated under routine programme conditions in a developing country.
Lefi, M, Mfinanga, S, Moshiro, C, Mugomela, A, O'Brien, R, van den Broek, J   +5 more
core  

Consumed by Abdominal Distention

Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

HIV-Negative Case of Talaromyces marneffei Pulmonary Infection with Liver Cirrhosis in China: A Case Report and Literature Review

Infection and Drug Resistance
Yu Liu,* Hongying Guo,* Wei Yuan, Ying Zou, Zhiping Qian, Xue Mei, Liujuan Ji, Jiefei Wang, Yuyi Zhang Department of Liver Intensive Care Unit, Shanghai Public Health Clinical Center, Fudan University, Shanghai, People’s Republic of China&ast ...
Liu Y, Guo H, Yuan W, Zou Y, Qian Z, Mei X, Ji L, Wang J, Zhang Y   +8 more
doaj  

Hepatitis C virus spread from HIV-positive to HIV-negative men who have sex with men.

PLoS ONE, 2018
The aim of this study was to evaluate the potential transmission of HCV strains between HIV-positive men who have sex with men (MSM) and HIV-negative MSM. Since 2000, an ongoing epidemic of HCV infections is observed among HIV-positive MSM in high-income
Caroline Charre, Laurent Cotte, Rolf Kramer, Patrick Miailhes, Matthieu Godinot, Joseph Koffi, Caroline Scholtès, Christophe Ramière   +7 more
doaj   +1 more source

The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development [PDF]

, 2017
Background: Men who have sex with men (MSM) experience significant inequalities in health and well-being. They are the group in the UK at the highest risk of acquiring a human immunodeficiency virus (HIV) infection.
Abraham, Aghaizu, Ajzen, Albarracín, Angus, Bailey, Bandura, Bartholomew, Becker, Bedoya, Berg, Berg, Berg, Blas, Borrelli, Borrelli, Bourne, Bourne, Bourne, Bowen, Bowen, Brady, British Association for Sexual Health & HIV, Brown, Bull, Cane, Carey, Carpenter, Carrico, Centers for Disease Control and Prevention, Chesney, Chiasson, Christensen, ClincalTrials.gov, ClincalTrials.gov, ClincalTrials.gov, Clutterbuck, Coffin, Cohen, Coia, Colfax, Conner, Craig, Crepaz, Crepaz, Das, Davidovich, Davidovich, DerSimonian, Desai, Dilley, Dilley, Dilley, Dilley, Dixon-Woods, Duan, Eaton, Eaton, Eaton, Elford, Ellis, European Centre for Disease Prevention and Control, Fisher, Fisher, Fletcher, Flowers, Flowers, Flowers, Flowers, Flowers, Forney, Frasca, French, Gardner, Gilbart, Glanz, Gold, Goodwin, Grantome, Gray, Guo, Hao, Health Protection Scotland, Herbst, Hidalgo, Higa, Higgins, Hightow-Weidman, Hightow-Weidman, Hirshfield, Hoaglin, Hosek, Hosek, Hosek, Huan, Hughes, Imrie, Janis, Jansen, Janz, Jbilou, Johnson, Johnson, Johnson, Johnson, Johnson, Jones, Kalichman, Kasatpibal, Kayser, Khosropour, Knussen, Ko, Koblin, Koblin, Landovitz, Lau, Lau, Lawson, Lorimer, Lu, Lucas, Macdonald, Malek, May, May, McKee, Melendez-Torres, Menza, Metcalf, Metcalf, Metsch, Michie, Michie, Michie, Michie, Michie, Mikolajczak, Mikolajczak, Mikolajczak, Miller, Mimiaga, Miranda, Moher, Morgenstern, Morgenstern, Murray, Mustanski, Mustanski, Nakagawa, Nakagawa, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, Neumann, New South Wales Sexually Transmitted Infection Program Unit, NHS Healthcare Improvement Scotland, Noar, Noar, Olander, Operario, Outlaw, O’Donnell, Painter, Parsons, Pawson, Pawson, Pawson R, Phillips, Picciano, Picciano, Prestwich, Public Health England, Rashbrook, Read, Reback, Rees, Reeves, Rhodes, Rhodes, Robinson, Rosser, Rycroft-Malone, Safren, Santos, Schnall, Schwarzer, Shoptaw, Shoptaw, Shoptaw, Simms, Simms, Skarbinski, Strömdahl, Tan, Taylor, Tobin, Tracy, van Kesteren, Varney, Warner, Webb, Wilkerson, Williams, Williams, Wolfers, Wolitski, Wong, Ye, Yin, Young, Young, Zhang, Zule   +213 more
core   +3 more sources

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Case report: HIV negative isolated scrotal Kaposi's sarcoma

International Journal of Surgery Case Reports, 2014
Kaposi's sarcoma (KS) is a rare angioproliferative disorder of the vascular endothelium. The development of KS requires Human Herpes Virus 8 (HHV-8) infection. An associated HIV infection is usually seen. Isolated scrotal KS has rarely been reported. In this article, we present a case of KS that primarily involved the scrotum in a HIV negative patient ...
Özmen, Hamid, Baba, Dursun, Kaçağan, Coşkun, Kayıkçı, Ali, Çam, Kamil   +4 more
openaire   +3 more sources