Results 1 to 10 of about 2,267 (69)

Human immunodeficiency virus in Saudi Arabia: Current and future challenges

Journal of Infection and Public Health, 2023
Introduction: Understanding the pathophysiology of HIV infection has been crucial to the design of effective anti-viral strategies. HIV infection is declining worldwide due to early diagnosis and the effective long-term use of anti-retroviral therapy ...
Maha Al-Mozaini, Tahani Al-Rahabani, Qais Dirar, Tala Alashgar, Ali A. Rabaan, Waleed Murad, Jawaher Alotaibi, Abdulrahman Alrajhi   +7 more
doaj   +1 more source

Implementation of a Routine Screening Program for Latent Tuberculosis Infection among Patients with Acute Leukemia at a Canadian Cancer Center

Current Oncology, 2022
Background: Screening for latent tuberculosis infection (LTBI) in patients with hematological malignancy is recommended because of their increased risk of tuberculosis (TB). We assessed the utility of tuberculin skin test (TST) screening in patients with
Rbab Taha, Sagar Kothari, Farid Foroutan, Melissa Gitman, Vikas Gupta, Tram Nguyen, Coleman Rotstein   +6 more
doaj   +1 more source

HIV-2 Vpx neutralizes host restriction factor SAMHD1 to promote viral pathogenesis

Scientific Reports, 2021
SAMHD1, a human host factor found in myeloid cells which restricts HIV-1 replication. It depletes the dNTPs pool for viral cDNA syntheses, thus preventing the viral replication in the cells.
Ahlam Mohamed, Talal Bakir, Huda Al-Hawel, Ibtihaj Al-Sharif, Razan Bakheet, Lubna Kouser, Valarmathy Murugaiah, Maha Al-Mozaini   +7 more
doaj   +1 more source

Evaluation of two molecular detection platforms for gastroenteritis pathogens in treated sewage water in the Eastern province of Saudi Arabia

Scientific Reports, 2022
The ability to screen environmental water samples for gastroenteritis pathogens, particularly viruses remains challenging. Here, we investigated the presence of enteric viruses in treated sewage effluent water samples collected from a cooling tower in ...
Fawaz A. Al-Wohaib, Ibtihaj Al-Sharif, Hassan Al-Zain, Donna Murad, Layla Al-Harbi, Maha Al-Mozaini   +5 more
doaj   +1 more source

New Insights on CMV Management in Solid Organ Transplant Patients: Prevention, Treatment, and Management of Resistant/Refractory Disease

Infectious Diseases and Therapy, 2022
Cytomegalovirus (CMV) infection can have both direct and indirect effects after solid-organ transplantation, with a significant impact on transplant outcomes.
Camille Nelson Kotton, Nassim Kamar
doaj   +1 more source

Quantitative proteomics analysis reveals unique but overlapping protein signatures in HIV infections

Journal of Infection and Public Health, 2021
Background: Human immunodeficiency virus-1 (HIV-1) exploits human host factors to complete its life cycle. Hence, discovery of HIV-regulated host proteins markers would better our understanding of the virus life-cycle and its contribution to pathogenesis
Maha Al-Mozaini, Alhusain Alzahrani, Ibtihaj Alsharif, Zakia Shinwari, Magid Halim, Abdullah Alhokail, Abdulrahman Alrajhi, Ayodele Alaiya   +7 more
doaj   +1 more source

A diagnostically challenging case of pyelonephritis caused by Lactobacillus

Clinical Case Reports, 2022
Extracellular polysaccharides produced by Lactobacillus have been shown to stimulate the immune system, suppress reactivity to allergens, and protect from infections; these properties underlie the use of Lactobacillus in probiotic formulations and in the
Erika Hori, Michiyo Nakamura, Hiroshi Tamura   +2 more
doaj   +1 more source

Laryngeal Histoplasmosis in an Immunocompromised Host

Annals of Internal Medicine: Clinical Cases, 2022
Laryngeal histoplasmosis is a rare manifestation of histoplasmosis infection and presents as a diagnostic challenge. It has been documented to occur in immunocompromised and immunocompetent hosts.
Angelina K. Winbush, Rodolfo Alpizar-Rivas, Andrew Cameron, Ashley P. O'Connell Ferster, Ted Louie   +4 more
doaj   +1 more source

Necrotic lymphoma in a patient with post-transplantation lymphoproliferative disorder: ultrasonography and CT findings with pathologic correlation [PDF]

Ultrasonography, 2015
Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cm×4.3 cm located between
Minsu Lee, Sang Kyum Kim, Yong Eun Chung, Jin-Young Choi, Mi-Suk Park, Joon Seok Lim, Myeong-Jin Kim, Honsoul Kim   +7 more
doaj   +1 more source

Chronic Candida dubliniensis meningitis in a lung transplant recipient

Medical Mycology Case Reports, 2019
Candida spp. are common colonizers of the oral mucosa and respiratory tract in lung transplant recipients. Although thought to be non-pathogenic in most cases, donor derived infections related to Candida spp. have been described. Among the manifestations
Sabina Herrera, Paolo Pavone, Deepali Kumar, Lianne Singer, Atul Humar, Cecilia Chaparro, Shaf Keshavjee, Shahid Husain, Coleman Rotstein   +8 more
doaj   +1 more source