Results 41 to 50 of about 423,543 (284)

Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status

BMC Pulmonary Medicine, 2019
Background The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure rates according to HIV status for
Conor D. Tweed, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Lerato Mohapi, Michael E. Murphy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Stephen H. Gillespie   +13 more
doaj   +1 more source

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. [PDF]

, 2017
The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses ...
Abba, Al Kadah, Albasri, Carlton A. Evans, Cesar Ugarte-Gil, Chau, Daniela E. Kirwan, David A. J. Moore, de Noronha, Eduardo D. Matos, Eduardo Ticona, Eza, Gustavo Cerrillo, Hansen, Jaime Cok, Jon S. Friedland, José Luis Cabrera, Kirwan, Landis, Lawn, Moore, Moore, Muller, Ojo, Olu-Eddo, Olu-Eddo, Ondounda, Osores, Pangalis, Park, Richner, Robert H. Gilman, Silva, Sobonya, Sridhar, Sterling, Syed M. Hasan Rizvi   +36 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Diagnostic value of reverse transcription-quantitative PCR in skin pus specimens for HIV-negative talaromycosis marneffei

Guangxi Yike Daxue xuebao
Objective To evaluate the diagnostic value of reverse transcription-quantitative polymerase chain reaction (RT-qPCR) detection of skin pus specimens in HIV-negative patients with talaromycosis marneffei (TSM).
Lan HUANG, Qihua HUANG, Dongyan ZHENG, Weixuan WU, Kaisu PAN, Yanqing ZHENG, Wanqing LIAO, Cunwei CAO   +7 more
doaj   +1 more source

Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: uptake, use, and effectiveness in an open-label demonstration project in East Africa [version 2; referees: 2 approved]

Gates Open Research, 2018
Background: Pre-exposure prophylaxis (PrEP) can provide high protection against HIV infection and is a recommended intervention for HIV-negative persons with substantial HIV risk.  Demonstration projects conducted in diverse settings worldwide illustrate
Renee Heffron, Kenneth Ngure, Josephine Odoyo, Nulu Bulya, Edna Tindimwebwa, Ting Hong, Lara Kidoguchi, Deborah Donnell, Nelly R. Mugo, Elizabeth A. Bukusi, Elly Katabira, Stephen Asiimwe, Jennifer Morton, Susan Morrison, Harald Haugen, Andrew Mujugira, Jessica E. Haberer, Norma C. Ware, Monique A. Wyatt, Mark A. Marzinke, Lisa M. Frenkel, Connie Celum, Jared M. Baeten, The Partners Demonstration Project Team   +23 more
doaj   +1 more source

Outcomes of HIV-infected versus HIV-non-infected patients treated for drug-resistance tuberculosis: Multicenter cohort study. [PDF]

PLoS ONE, 2018
The emergence of resistance to anti-tuberculosis (DR-TB) drugs and the HIV epidemic represent a serious threat for reducing the global burden of TB. Although data on HIV-negative DR-TB treatment outcomes are well published, few data on DR-TB outcomes ...
Mathieu Bastard, Elisabeth Sanchez-Padilla, Philipp du Cros, Atadjan Karimovich Khamraev, Nargiza Parpieva, Mirzagaleg Tillyashaykov, Armen Hayrapetyan, Kamene Kimenye, Shazina Khurkhumal, Themba Dlamini, Santiago Fadul Perez, Alex Telnov, Cathy Hewison, Francis Varaine, Maryline Bonnet   +14 more
doaj   +1 more source

First detection of intestinal microsporidia in Northern Nigeria [PDF]

, 2005
Microsporidia are intracellular spore-forming protozoa that are increasingly being recognized as pathogens in humans. Faecal samples were taken from 2250 HIV/AIDS and 1050 HIV-negative patients from Kano and Makurdi in Northern Nigeria, and were ...
A B, Yako, D D, Duhlinska, G I, Anyanwu, I CJ, Omalu, P U, Inyama, V A, Pam   +5 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Are HIV-infected people at risk group for COVID-19 morbidity and severe course?

Инфекция и иммунитет
Opinions regarding the frequency and severity of COVID-19 clinical course in HIV-infected vs. HIV-negative people are controversial. The study was aimed to assess the incidence and severity of COVID-19 clinical course in HIV-infected people in comparison
V. I. Sergevnin, Marina V. Rozhkova
doaj   +1 more source

The effect of HIV status on perinatal outcome at Mowbray Maternity Hospital and referring MOUs [PDF]

, 2011
Includes bibliographical referencesBackground: 33,4 Million people were living with the Human Immune Deficiency virus by the end of 2009 with sub-Saharan Africa the most affected region.
Kennedy, Deon
core