Results 111 to 120 of about 2,775,555 (408)
Advanced Science, EarlyView.This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang +8 more
wiley +1 more source
HIV, TB and ART: the CD4 enigma [PDF]
arXiv, 2012 The concentration of CD4 T-lymphocytes (CD4 count), in a person's plasma is widely used to decide when to start HIV-positive people on anti-retroviral therapy (ART) and to predict the impact of ART on the future course of HIV and tuberculosis (TB). However, CD4 cell-counts vary widely within and among populations and depend on many factors besides HIV ...
arxiv
Surveillance, Stigma & Sociotechnical Design for HIV [PDF]
arXiv, 2020 Online dating and hookup platforms have fundamentally changed people's day-to-day practices of sex and love-but exist in tension with older social and medicolegal norms. This is particularly the case for people with HIV, who are frequently stigmatized, surveilled, ostracized and incarcerated because of their status.
arxiv
BMC Research Notes, 2018 Objectives The Botswana tuberculosis HIV Knowledge Attitude and Practice study sought to assess knowledge, attitudes and practices of communities on TB and identify sources of their information on this disease and HIV.
Godfrey Musuka +9 more
doaj +1 more source
Mental health and HIV/AIDS: the need for an integrated response
AIDS (London), 2019 Tremendous biomedical advancements in HIV prevention and treatment have led to aspirational efforts to end the HIV epidemic. However, this goal will not be achieved without addressing the significant mental health and substance use problems among people ...
R. Remien +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao +13 more
wiley +1 more source
A Joint Spatial Conditional Auto-Regressive Model for Estimating HIV Prevalence Rates Among Key Populations [PDF]
arXiv, 2020 Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy decisions, especially for key populations that are at higher risk for HIV infection.
arxiv
Journal of the International AIDS SocietyIntroduction Men who have sex with men (MSM), especially those living with HIV, are at an increased risk of anal cancer. The prevalence and incidence of its precursor, anal high‐grade squamous intraepithelial lesions (HSILs), among MSM who started ...
Supanat Thitipatarakorn +16 more
doaj +1 more source
Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017
Nature, 2019 HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has demonstrated that there is substantial local variation in the prevalence of HIV; however, subnational variation has not been investigated at a high spatial ...
L. Dwyer-Lindgren +40 more
semanticscholar +1 more source
Advanced Science, EarlyView.The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...
Lu Zhao +10 more
wiley +1 more source