Results 91 to 100 of about 1,287,797 (309)

FastPrEP: a protocol to evaluate uptake, coverage, and effectiveness of a youth-focused, decentralised and differentiated district-wide HIV pre-exposure prophylaxis program

BMC Public Health
Background Adolescents and young people (AYP) are at increased risk of HIV acquisition and onward transmission in South Africa. The benefits of oral pre-exposure prophylaxis (PrEP) are well established, however, epidemic impact depends on access ...
E Rousseau, DJ Davey, LS Fynn, M Wallace, P Macdonald, C Pike, N Mathola, F Little, K Lebelo, LG Bekker   +9 more
doaj   +1 more source

Evidence of HIV treatment and viral suppression in preventing the sexual transmission of HIV [PDF]

People with HIV who take HIV medicine as prescribed and get and keep an undetectable viral load have effectively no risk of transmitting HIV to their HIV-negative sexual partners.cdc-hiv-art-viral-suppression ...

core  

Postnatal retention in HIV care: insight from the Swiss HIV Cohort Study over a 15-year observational period. [PDF]

, 2015
OBJECTIVES The aim of this study was to quantify loss to follow-up (LTFU) in HIV care after delivery and to identify risk factors for LTFU, and implications for HIV disease progression and subsequent pregnancies.
K Aebi‐Popp, Aebi-Popp, K, Aebi-Popp, K., Rickenbach, M, M Cavassini, Martinez de Tejada, B., E Bernasconi, C Thorne, Cavassini, M, J Fehr, Rudin, C., K Aebi-Popp, Lecompte, Thomas Pierre, Bertisch, B, C Grawe, Lecompte, T D, T D Lecompte, Kouyos, R., Stoeckle, M., Bertisch, Barbara, Thorne, C, R Kouyos, I Hoesli, Rudin, C, Martinez de Tejada, B, Fehr, J, Dr Karoline Aebi-Popp, C Rudin, Bernasconi, E., TD Lecompte, Staehelin, C., M Stoeckle, Thorne, C., Cavassini, M., Stoeckle, M, Martinez De Tejada Weber, Begona, C Staehelin, Bernasconi, E, Hoesli, I, Bertisch, B., Bernasconi, Enos, Aebi-Popp, Karoline, Kouyos, R, Rickenbach, M., Staehelin, C, Lecompte, T.D., B Bertisch, Grawe, C, Grawe, C., Hoesli, I., Stähelin, Cornelia Johanna, Fehr, J., B Martinez De Tejada, M Rickenbach   +53 more
core   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

Advanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad, Anastasiia Steksova, Yuyang Tang, Leyao Huang, Alireza Velayati, Shengwei Zhang, Aditi Dey Poonam, Sina Jamalzadegan, Matthew Breen, Hongjie Chen, Mahsa Bagi, Guochun Jiang, Qingshan Wei   +12 more
wiley   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Management of mental health disorders in HIV-positive patients

Southern African Journal of HIV Medicine, 2013
These guidelines are intended as a reference document to assist HIV nurse and doctor clinicians in managing mental health disorders. It is intended to improve awareness, knowledge and capacity to support patients living with HIV and mental health ...
Southern African HIV Clinicians Society
doaj   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

A Standardized workflow for Orthohantavirus production, detection, and antiviral screening

Virology Journal
Background Orthohantaviruses are zoonotic RNA viruses that cause hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. Their slow replication, lack of cytopathic effects, and variable biosafety requirements have long hindered the
Hannah S. Schwarzer-Sperber, Tamara Mussfeldt, Julia Boesner, Tina Dluzak, Kathrin Sutter, Roland Schwarzer   +5 more
doaj   +1 more source

Complications of high volume circumcision: glans amputation in adolescents; a case report

BMC Urology, 2019
Background The past four years has seen a rapid roll-out of male medical circumcision services in South Africa in response to clinical trials showing circumcision prevents HIV acquisition in heterosexual men.
Mmatsie Manentsa, Hilary Mukudu, Nthabiseng Koloane, Ashley Ringane, Eleanor Matta, Neil A. Martinson, Limakatso Lebina   +6 more
doaj   +1 more source

The relationship between HIV seroconversion illness, HIV test interval and time to AIDS in a seroconverter cohort. [PDF]

, 2003
Seroconversion illness is known to be associated with more rapid HIV disease progression. However, symptoms are often subjective and prone to recall bias.
UK Register of HIV Seroconverters, UK, Gillett, J, Tyrer, F, Porter, K, Walker, AS   +4 more
core