Results 81 to 90 of about 1,322,023 (308)

Knowledge, attitude and practice towards Coronavirus disease 2019 prevention in Ethiopia: Systematic review and meta-analysis

Journal of Biostatistics and Epidemiology, 2021
Background: Level of knowledge, attitude and practice (KAP) of the community towards corona virus disease 2019 (COVID-19) is important to prevent and control the disease .
Dinka Fikadu Gamtesa, Habteyes Hailu Tola, Gadissa Gutema, Biniyam Dagne, Bira Bejiga Bedassa   +4 more
doaj  

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Chemsex, sexualized drug use and emotional vulnerability among men who have sex with men (MSM): a one-month survey in a STI/HIV center

BMC Public Health
Background Chemsex, characterized by the intentional use of specific drugs to enhance sexual experiences during group sessions, represents a challenge for the health of some sexually active communities, such as men who have sex with men (MSM).
Stella Capodieci, Mauro Zaccarelli, Christof Stingone, Eugenia Giuliani, Valentina Cafaro, Laura Gianserra, Maria Gabriella Donà, Alessandra Latini, Massimo Giuliani   +8 more
doaj   +1 more source

Efficacy and improvement of lipid profile after switching to rilpivirine in resource limited setting: real life clinical practice

AIDS Research and Therapy, 2019
Background Long-term success of cART is possible if the regimen is convenient and less-toxic. This study assessed the efficacy and safety of switching from a first-line NNRTI or boosted PI-based regimens to RPV-based regimens among virologically ...
Sivaporn Gatechompol, Anchalee Avihingsanon, Tanakorn Apornpong, Win Min Han, Stephen J. Kerr, Kiat Ruxrungtham   +5 more
doaj   +1 more source

DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction

Advanced Science, EarlyView.
Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li, Yiman Liu, Liya Liang, Rongming Liu   +3 more
wiley   +1 more source

HIV and and transgender people

HIV Diagnoses in the US, 2009-20142,351 TRANSGENDER PEOPLE RECEIVED AN HIV DIAGNOSIS. OF THESE:\u2022 84% WERE TRANSGENDER WOMEN\u2022 15% WERE TRANSGENDER MEN*\u2022 ABOUT HALF LIVED IN THE SOUTHcdc-hiv-transgender-factsheet ...

core   +1 more source

FastPrEP: a protocol to evaluate uptake, coverage, and effectiveness of a youth-focused, decentralised and differentiated district-wide HIV pre-exposure prophylaxis program

BMC Public Health
Background Adolescents and young people (AYP) are at increased risk of HIV acquisition and onward transmission in South Africa. The benefits of oral pre-exposure prophylaxis (PrEP) are well established, however, epidemic impact depends on access ...
E Rousseau, DJ Davey, LS Fynn, M Wallace, P Macdonald, C Pike, N Mathola, F Little, K Lebelo, LG Bekker   +9 more
doaj   +1 more source

Resurgence of HIV infection among men who have sex with men in Switzerland : mathematical modelling study [PDF]

, 2012
New HIV infections in men who have sex with men (MSM) have increased in Switzerland since 2000 despite combination antiretroviral therapy (cART). The objectives of this mathematical modelling study were: to describe the dynamics of the HIV epidemic in ...
Steven Derendinger (134735), Swiss HIV, Cohort Study, Glass, T. R., Fraser, C., Steven Derendinger, Christophe Fraser (7754), Vernazza, P., Frank de Wolf, Ard van Sighem (134719), Beatriz Vidondo (134721), Martin Gebhardt, Swiss HIV Cohort Study, Beatriz Vidondo, de Wolf Frank, Derendinger Steven, van Sighem, Ard, Jeannin André, Vernazza Pietro, Heiner C Bucher, Low, N., Martin Gebhardt (134732), Nicola Low (62560), Vidondo, B., Derendinger, Steven, Pietro Vernazza (82546), De Wolf, F., Bucher, Heiner C., Bezemer, D., Tracy R. Glass (134725), Bezemer, Daniela, Jeannin, André, Gebhardt, Martin, Bucher Heiner C., Tracy R Glass, de Wolf, Frank, Vidondo, Beatriz, Heiner C. Bucher (134728), Christophe Fraser, Jeannin, A., Daniela Bezemer, Gebhardt Martin, Bezemer Daniela, Bucher, H. C., Glass, Tracy R., Pietro Vernazza, Low Nicola, van Sighem Ard, André Jeannin, Daniela Bezemer (134739), Nicola Low, Glass Tracy R., Fraser, Christophe, Derendinger, S., Vidondo Beatriz, Ard van Sighem, Gebhardt, M., André Jeannin (134737), Frank de Wolf (89583), Fraser Christophe, Vernazza, Pietro, Low, Nicola, Van Sighem, A., Glass, T.R., Bucher, H.C.   +63 more
core   +2 more sources

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source