Results 111 to 120 of about 1,322,023 (308)
Introduction Men who have sex with men (MSM), especially those living with HIV, are at an increased risk of anal cancer. The prevalence and incidence of its precursor, anal high‐grade squamous intraepithelial lesions (HSILs), among MSM who started ...
Supanat Thitipatarakorn +16 more
doaj +1 more source
Decreasing Deaths Among People with HIV [PDF]
About 1.2 million people are living with HIV in the United States. Improvements in HIV care and treatment have made it possible for people with HIV to live nearly as long as people who don\u2019t have HIV. Yet, in 2017 HIV was among the 10 leading causes
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Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman +11 more
wiley +1 more source
Background Accurate and timely cause of death information is important for public health monitoring. In recent years, deaths with an unknown/ill-defined underlying cause have increased markedly in Canada, particularly in British Columbia (BC), among ...
Ly Nguyen +9 more
doaj +1 more source
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley +1 more source
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey +13 more
wiley +2 more sources
At the end of 2010, one in four people living with HIV in the United States were women. Black/African American and Hispanic/ Latino women continue to be disproportionately affected by HIV, compared with women of other races/ethnicities.
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Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné +3 more
wiley +1 more source
The Nature of Cell‐Penetrating Poly(disulfide)s
The mode of action of cell‐penetrating poly(disulfide)s (CPDs) is elucidated to understand thiol‐mediated uptake (TMU) in general and guide future efforts to control cellular entry for chemicals delivery and pathogen defense. ABSTRACT Cell‐penetrating poly(disulfide)s (CPDs) are the most popular thiol‐mediated uptake (TMU) tools for delivering attached
Saidbakhrom Saidjalolov +7 more
wiley +2 more sources

