Results 151 to 160 of about 2,775,555 (408)

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

An Evaluation on the Role of Non-Coding RNA in HIV Transcription and Latency: A Review [PDF]

arXiv
The existence of latent cellular reservoirs is recognized as the major barrier to an HIV cure. Reactivating and eliminating "shock and kill" or permanently silencing "block and lock" the latent HIV reservoir, as well as gene editing, remain promising approaches, but so far have proven to be only partially successful.
arxiv  

Probability-Scale Residuals in HIV/AIDS Research: Diagnostics and Inference [PDF]

Quantitative Methods for HIV/AIDS Research, 2017, edited by Chan C, Hudgens MG, Chow SC, 2018
The probability-scale residual (PSR) is well defined across a wide variety of variable types and models, making it useful for studies of HIV/AIDS. In this manuscript, we highlight some of the properties of the PSR and illustrate its application with HIV data.
arxiv  

Where have all the susceptible gonococci gone? A historical review of changes in MIC distribution over the past 75 years

BMC Infectious Diseases, 2019
Background Does the emergence of antimicrobial resistance in Neisseria gonorrhoeae include the erasure of highly susceptible strains or does it merely involve a stretching of the MIC distribution?
Chris Kenyon, Jolein Laumen, Dorien Van Den Bossche, Christophe Van Dijck   +3 more
doaj   +1 more source

The HIV-associated tuberculosis epidemic--when will we act?

, 2010
Despite policies, strategies, and guidelines, the epidemic of HIV-associated tuberculosis continues to rage, particularly in southern Africa. We focus our attention on the regions with the greatest burden of disease, especially sub-Saharan Africa, and ...
Chimzizi, Rhehab, Corbett, Elizabeth L, De Cock, Kevin M, Harries, Anthony D, Harrington, Mark, Lawn, Stephen D, Maher, Dermot, Santos-Filho, Ezio T, Williams, Brian G, Zachariah, Rony   +9 more
core   +1 more source

Transcription‐independent functions of p53 in DNA repair pathway selection

BioEssays, Volume 45, Issue 1, January 2023., 2023
Transcription‐independent early recruitment and PARylation of p53 at DNA damage sites promotes the recruitment of particular repair factors (e.g. DDB1 and 53BP1) and thereby tipping the balance of repair pathway selection. Abstract Recently discovered transcription‐independent features of p53 involve the choice of DNA damage repair pathway after ...
Yu‐Hsiu Wang, Michael P. Sheetz
wiley   +1 more source

Evaluating the impact of PrEP on HIV and gonorrhea on a networked population of female sex workers [PDF]

arXiv, 2019
Sexual contacts are the main spreading route of HIV. This puts sex workers at higher risk of infection even in populations where HIV prevalence is moderate or low. Alongside condom use, Pre-Exposure Prophylaxis (PrEP) is an effective tool for sex workers to reduce their risk of HIV acquisition.
arxiv  

Management of mental health disorders in HIV-positive patients

Southern African Journal of HIV Medicine, 2013
These guidelines are intended as a reference document to assist HIV nurse and doctor clinicians in managing mental health disorders. It is intended to improve awareness, knowledge and capacity to support patients living with HIV and mental health ...
Southern African HIV Clinicians Society
doaj   +1 more source

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells [PDF]

, 2018
The persistence of HIV reservoirs, including latently infected, resting CD4+ T cells, is the major obstacle to cure HIV infection. CD32a expression was recently reported to mark CD4+ T cells harboring a replication-competent HIV reservoir during ...
Abdel-Mohsen, Mohamed, Betts, Michael R., Buzon, Maria J., Castellvi, Josep, Cox, Kara, Del Rio Estrada, Perla M., Frank, Ian, Genesca, Meritxell, Giron, Leila B., Gonzalez-Navarro, Mauricio, Grau-Exposito, Judith, Hazuda, Daria, Howell, Bonnie, King, Collin T., Kostman, Jay, Kuri-Cervantes, Leticia, Li, Qingsheng, Lynn, Kenneth, Martinez-Picado, Javier, Montaner, Luis J., Mounzer, Karam, Nell, Racheal A., Paiardini, Mirko, Planelles, Vicente, Reyes-Teran, Gustavo, Richman, Douglas, Serra-Peinado, Carla, Spivak, Adam M., Tebas, Pablo, Tomescu, Costin, Vadrevu, Surya Kumari, Vemula, Sai, Wan, Yanmin, Wu, Guoxin   +33 more
core   +1 more source

Copper‐Catalyzed Synthesis of C‐2 Substituted Indolin‐3‐Ones and Indolin‐3‐One [4+2] Cycloadducts Through Azide‐Tethered Iodonium Ylides

Asian Journal of Organic Chemistry, EarlyView.
Azide‐tethered iodonium ylides under copper catalysis generate metallocarbenes that undergo intramolecular trapping by the azide moiety and generate a reactive C‐acylimine, effectively coupling two nucleophilic centers. This intermediate can be trapped by a wide range of nucleophiles or 1,3‐dienes producing complex indolin‐3‐ones and ...
Israel Najar Guerrero, Zinah Al‐Khateeb, F. G. West   +2 more
wiley   +1 more source