Results 221 to 230 of about 1,322,023 (308)

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah   +4 more
wiley   +1 more source

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Diqin Yan   +6 more
wiley   +1 more source

Unbound Intrinsic Formation Clearance of 6β‐Hydroxycortisol Is a Useful Biomarker of CYP3A4 Activity during Pregnancy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pregnancy results in multiple physiological changes that impact drug disposition. For example, hepatic CYP3A activity and renal transporter‐mediated clearance increase in late pregnancy, but the time course of these changes across pregnancy is not known.
Aurora K Authement   +3 more
wiley   +1 more source

The Global HIV/AIDS Vaccine Enterprise: scientific strategic plan.

open access: yesPLoS Medicine, 2005
Global HIV/AIDS Vaccine Enterprise
doaj   +1 more source

Clinical Pharmacology in Transgender Medicine: What Gaps Remain?

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Mechanistic information is limited about the effects of gender‐affirming hormone therapy and the unique factors that influence the absorption, distribution, metabolism, and excretion properties of medications across therapeutic classes for transgender people.
Lauren R. Cirrincione
wiley   +1 more source

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

open access: yesClinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila   +5 more
wiley   +1 more source

The Influence of Ethical Ideologies on Corporate Social Performance in Small and Medium‐Sized Enterprises in the United Kingdom

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Research addressing the microfoundations of corporate social performance (CSP) in small and medium‐sized enterprises (SMEs) remains sparse. This paper aims to investigate how SME managers' ethical ideology affects CSP and examines the mediating role of their CSR orientation (CSRO): economic, legal, ethical, and philanthropic.
Sarah Mohammad Suleiman Alsyoof   +2 more
wiley   +1 more source

Mobile Wellness in the Workplace: Addressing the Global Men’s Healthcare Gap, from a World Health Organization Framework Perspective

open access: yesJournal of Epidemiology and Global Health
Stephanie Davis   +3 more
doaj   +1 more source

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