Results 31 to 40 of about 1,402,138 (245)

Nutrition Guidelines for HIV-infected Adults and Children in Southern Africa

open access: yesSouthern African Journal of HIV Medicine, 2007
No abstract available.
D. C. Spencer   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Retention in primary care among unstably housed residents of a low-income, inner-city neighborhood with a high prevalence of substance use and related disorders

open access: yesInternational Journal for Equity in Health
Introduction Access to and engagement with primary healthcare can be difficult for marginalized low-income populations residing in inner cities in high-income countries.
M. Gumprich   +17 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Identifying hospitalization episodes of care among people with and without HIV in British Columbia, Canada

open access: yesBMC Medical Research Methodology
Background Hospitalizations are a resource-intensive form of healthcare use, particularly for persons with chronic conditions such as HIV. In standardized Canadian hospitalization databases, it can be unclear whether a hospitalization record is an ...
SD Emerson   +11 more
doaj   +2 more sources

The natural history of anal cancer-associated human papillomavirus infection among cisgender men and transgender women who have sex with men in an acute HIV cohort in Thailand

open access: yesBMC Infectious Diseases
Introduction Anal cancer-associated human papillomavirus (caHPV) infection is the leading cause of anal cancer. This study describes human papillomavirus (HPV) progression among participants with acute HIV acquisition.
Supanat Thitipatarakorn   +17 more
doaj   +1 more source

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

open access: yesRetrovirology, 2006
Chronic activation of the immune system is a hallmark of progressive HIV infection and better predicts disease outcome than plasma viral load, yet its etiology remains obscure.
J. Brenchley
semanticscholar   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Poxvirus Vectors Activate Human NK and MAIT Cells in a Type I Interferon, IL-18, and Monocyte-Dependent Manner

open access: yesJournal of Immunology Research
Recombinant poxviruses have been extensively studied as vaccine vectors, yet the specific mechanisms by which they engage the immune system remain incompletely understood.
Kombo F. N’guessan   +7 more
doaj   +1 more source

The impact of HIV infection on clinical presentation and mortality among persons with hepatocellular carcinoma in Kampala, Uganda

open access: yesBMC Infectious Diseases, 2023
Background HIV infection is associated with more rapid progression of some comorbidities. This study assessed the impact of HIV-infection on the presentation and outcome of HCC.
Sara K. Nsibirwa   +5 more
doaj   +1 more source

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