Results 41 to 50 of about 1,322,023 (308)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

HIV/AIDS in Kansas, Annual Report, ... HIV/AIDS in Kansas, Annual Report for Calendar Year ... ... AIDS Annual Tables

, 2009
"Sources of information for this report: Kansas HIV/AIDS Surveillance System (eHARS)"HIV/AIDS in Kansas, Annual Report, December 2009 HIV/AIDS in Kansas, Annual Report, December 2010 HIV/AIDS in Kansas, Annual Report, December 2011 HIV/AIDS in ...
Kansas. HIV/AIDS Surveillance Program
core   +1 more source

Effectiveness, Sex Differences, and Patient Experience in Real-World Use of Long-Acting Cabotegravir and Rilpivirine: Results from a Prospective Study

Infectious Diseases and Therapy
Introduction Long-acting intramuscular cabotegravir plus rilpivirine (LA-CAB/RPV) administered every 2 months (Q2M) has been available in Spain since January 2023 as a switch strategy for HIV treatment.
Ana González-Cordón, Júlia Calvo, Leire Berrocal, Maite León-Fabo, Maria Martínez-Rebollar, Ivan Chivite, Alexy Inciarte, Paula Arreba, Juan Ambrosioni, Lorena de la Mora, Pilar Callau, Alberto Foncillas, Abiu Sempere, José Luis Blanco, Esteban Martinez, Jose M. Miro, Roger Llobet, Elisa de Lazzari, Josep Mallolas, Montserrat Laguno, Berta Torres   +20 more
doaj   +1 more source

Evolution of Risk Behaviors, Sexually Transmitted Infections and PrEP Care Continuum in a Hospital-Based PrEP Program in Barcelona, Spain: A Descriptive Study of the First 2 Years’ Experience

Infectious Diseases and Therapy, 2022
Introduction Pre-exposure prophylaxis (PrEP) is effective for HIV prevention, but the PrEP care continuum also involves improving PrEP awareness, uptake, adherence, and retention in care.
Ainoa Ugarte, Lorena de la Mora, David García, María Martínez-Rebollar, Elisa de Lazzari, Berta Torres, Alexy Inciarte, Juan Ambrosioni, Iván Chivite, Estela Solbes, Nicolás de Loredo, Guillermo Federico Del Carlo, Ana González-Cordón, José Luis Blanco, Esteban Martínez, Josep Mallolas, Montserrat Laguno   +16 more
doaj   +1 more source

Concurrent sexual partnerships and HIV prevalence in five urban communities of sub-Saharan Africa. [PDF]

, 2001
OBJECTIVE: To estimate parameters of concurrent sexual partnerships in five urban populations in sub-Saharan Africa and to assess their association with levels of HIV infection and other sexually transmitted infections (STI).
Lagarde, E., Ferry, B., N'Doye, I., Sukwa, T, Buvé, A, Laourou, M, Akam, E, Sukwa, T., Chege, J, N'Doye, I, Auvert, B, Maury, B, Morison, L., Caraël, M, Maury, E., Lagarde, E, Auvert, B., Chege, J., Buvé, A., Study Group on Heterogeneity of HIV Epidemics in African Cities, Caraël, M., Akam, E., Laourou, M., Ferry, B, Morison, L   +24 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The natural history of anal cancer-associated human papillomavirus infection among cisgender men and transgender women who have sex with men in an acute HIV cohort in Thailand

BMC Infectious Diseases
Introduction Anal cancer-associated human papillomavirus (caHPV) infection is the leading cause of anal cancer. This study describes human papillomavirus (HPV) progression among participants with acute HIV acquisition.
Supanat Thitipatarakorn, Sujittra Suriwong, Siriporn Nonenoy, Aphakan Klinsukontakul, Jirat Makphol, Sumitr Tongmuang, Piranun Hongchookiat, Napasawan Chinlaertworasiri, Pravit Mingkwanrungruang, Carlo Sacdalan, Kultida Poltavee, Nitiya Chomchey, Tippawan Pankam, Stephen J. Kerr, Reshmie Ramautarsing, Donn Colby, Nipat Teeratakulpisarn, Nittaya Phanuphak   +17 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Poxvirus Vectors Activate Human NK and MAIT Cells in a Type I Interferon, IL-18, and Monocyte-Dependent Manner

Journal of Immunology Research
Recombinant poxviruses have been extensively studied as vaccine vectors, yet the specific mechanisms by which they engage the immune system remain incompletely understood.
Kombo F. N’guessan, Zhanna Shubin, Kawthar Machmach, Johan K. Sandberg, Julie A. Ake, Sandhya Vasan, Michael A. Eller, Dominic Paquin-Proulx   +7 more
doaj   +1 more source

Nutrition Guidelines for HIV-infected Adults and Children in Southern Africa

Southern African Journal of HIV Medicine, 2007
No abstract available.
D. C. Spencer, C. Harman, T. Naicker, S. Gohre   +3 more
doaj   +1 more source