Results 81 to 90 of about 2,775,555 (408)

CD4 intragenic SNPs associate with HIV-2 plasma viral load and CD4 count in a community-based study from Guinea-Bissau, West Africa. [PDF]

, 2010
OBJECTIVES: The human genetics of HIV-2 infection and disease progression is understudied. Therefore, we studied the effect of variation in 2 genes that encode products critical to HIV pathogenesis and disease progression: CD4 and CD209.
Aaby, Peter, Bisseye, Cyrille, Edwards, Todd L, Hennig, Branwen J, Hill, Adrian V, Jaye, Assan, Kaye, Steve, Novelli, Giuseppe, Schim van der Loeff, Maarten F, Scott, William K, Sirugo, Giorgio, Tacconelli, Alessandra, Velez-Edwards, Digna R, Whittle, Hilton C, Williams, Scott M   +14 more
core   +2 more sources

Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives

Advanced Sensor Research, EarlyView.
This review delves deeply into the various types of optical microfiber biosensors, grounded firmly in their fundamental principles, and underscores their indispensable roles in pushing forward biomedical advancements. It examines the latest advancements, challenges faced by these biosensors in practical applications, future directions, breakthroughs ...
Lili Liang, Fei Xie, Li Jin, Bowen Yang, Li‐Peng Sun, Bai‐Ou Guan   +5 more
wiley   +1 more source

Fluorine‐Directed Automated Mannoside Assembly

Angewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023
Motivated by the importance of fluorination in drug discovery, fluorine‐directed automated glycan assembly (AFGA) is disclosed. This strategy leverages the C(sp3)−F bond at C2 to enable α‐stereocontrolled glycosylation that eliminates the reliance on O‐based directing groups.
Charlotte S. Teschers, Ryan Gilmour
wiley   +1 more source

Syphilis serology in HIV-positive and HIV-negative Nigerians: The public health significance [PDF]

, 2006
Syphilis has acquired new potential for morbidity and mortality through association with increased risk for HIV infection. Case-control survey was conducted using Rapid Plasma Reagin test and confirmatory Immunochromatographic test among HIV-positive ...
Alo, Moses, Ariom, Thaddeus, Ogbu, Ogbonnaya, Uneke Jesse, Chigozie   +3 more
core   +1 more source

AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid. [PDF]

, 2007
BACKGROUND: Surfactant protein D (SP-D) and Mannose Binding Lectin (MBL) are collectins that have opsonic and immunoregulatory functions, are found in lung fluid and interact with the human immunodeficiency virus (HIV).
French, Neil, Gordon, Stephen B, Jambo, Kondwani C, Zijlstra, Ed   +3 more
core   +2 more sources

HIV and AIDS

DeckerMed Family Medicine, 2021
In the quarter-century since the first report of AIDS in the United States, HIV infection has spread throughout the population, disproportionately affecting black women, Hispanic women, and men who have sex with men. The prognosis for persons infected with HIV has improved dramatically with the introduction and evolution of highly active antiretroviral
openaire   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source

Docking Studies on HIV Integrase Inhibitors Based On Potential Ligand Binding Sites [PDF]

International Journal on Bioinformatics & Biosciences, vol. 2, pp. 21-29, 2012, 2012
HIV integrase is a 32 kDa protein produced from the C-terminal portion of the Pol gene product, and is an attractive target for new anti-HIV drugs. Integrase is an enzyme produced by a retrovirus (such as HIV) that enables its genetic material to be integrated into the DNA of the infected cell.
arxiv   +1 more source

Knowledge, attitude and practice towards Coronavirus disease 2019 prevention in Ethiopia: Systematic review and meta-analysis

Journal of Biostatistics and Epidemiology, 2021
Background: Level of knowledge, attitude and practice (KAP) of the community towards corona virus disease 2019 (COVID-19) is important to prevent and control the disease .
Dinka Fikadu Gamtesa, Habteyes Hailu Tola, Gadissa Gutema, Biniyam Dagne, Bira Bejiga Bedassa   +4 more
doaj  

Efficacy and improvement of lipid profile after switching to rilpivirine in resource limited setting: real life clinical practice

AIDS Research and Therapy, 2019
Background Long-term success of cART is possible if the regimen is convenient and less-toxic. This study assessed the efficacy and safety of switching from a first-line NNRTI or boosted PI-based regimens to RPV-based regimens among virologically ...
Sivaporn Gatechompol, Anchalee Avihingsanon, Tanakorn Apornpong, Win Min Han, Stephen J. Kerr, Kiat Ruxrungtham   +5 more
doaj   +1 more source