Results 181 to 190 of about 156,550 (306)

CAR-T Cell Therapy for HIV Cure: Current Challenges, Advances and Future Directions. [PDF]

Viruses
Padurariu-Covit MD, Georgescu C, Andreescu M, Chiscop I, Plesea-Condratovici C, Arbune M.   +5 more
europepmc   +1 more source

HIV CURE PROPOSAL

This therapy involves the use of ozone infused nanobubbles to deliver controlled low dose ROS which is lethal to virus but harmless to humans due to powerful antioxidants in the body and made made antioxidants including catalase which breaks down excessive ROS just in case it's produced.Ozone infused nanobubbles is proven virucidal and therefore kills ...
openaire   +2 more sources

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo, Sarah N. Hilmer, David J. Hunter, Stephanie Mathieson, Riyaas Mohamed, Leo Li, Natalie Fung, Anthony Yue, Manuela L. Ferreira   +8 more
wiley   +1 more source

In pursuit of an HIV cure: from stem cell transplants to gene therapies. [PDF]

Front Genome Ed
Clees J, Basic M, Cruz PE, Ramirez SH, Andrews AM.   +4 more
europepmc   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

HIV cure research contributions from Africa in the last three decades. [PDF]

Front Immunol
Nakanjako D, Kankaka EN, Lungu C, Galiwango RM, Reynolds SJ, Mahmoudi T, Ndung'u T.   +6 more
europepmc   +1 more source

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

Clinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila, Mugia B. Rahardja, Puguh Prasetyoputra, Anne A. Suwargiani, Yanu E. Prasetyo, Eriska Riyanti   +5 more
wiley   +1 more source

Targeting HIV myeloid and central nervous system reservoirs for HIV cure. [PDF]

Curr Opin HIV AIDS
Grasberger P, Clayton KL.
europepmc   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

The SMAC mimetic AZD5582 reverses HIV latency as a single agent in resting primary CD4+ T cells

Journal of Virus Eradication, 2019
G. Sampey, D. Irlbeck, E. Browne, M. Kanke, E. Cule, S. Wills, S. Falcinelli, Z. Wang, J. Kircherr, B. Allard, E. Stuelke, K. Sholtis, R. Ferris, J. Brehm, D. Favre, J.-P. Routy, C. Jones, N. Archin, D. Margolis, R. Dunham   +19 more
doaj   +1 more source