Results 181 to 190 of about 2,617,462 (305)

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter   +10 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

open access: yesBiological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad   +5 more
wiley   +1 more source

A Closer Look at Rape Myth Beliefs Among University Students: Comparisons and Correlates Based on Field and Stage of Study, Victimisation Experiences, Demographics and Psychological Traits

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT Disproportionate rates of sexual violence occur among university students, with rape culture and misconceptions about consent prevalent. To comprehensively examine rape myth beliefs among different student groups, 417 UK University students enrolled on courses in four distinct disciplinary areas; social sciences (n = 131), applied sciences (n =
Dominic Willmott   +6 more
wiley   +1 more source

Mycobacterial infections and HIV

open access: yesCurrent Opinion in Infectious Diseases, 1993
openaire   +2 more sources

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