Results 21 to 30 of about 69,995 (125)
Modeling TB-HIV syndemic and treatment [PDF]
J. Appl. Math. 2014 (2014), Art. ID 248407, 14 pp, 2014 Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered a deadly human syndemic. In this article, we formulate a model for TB and HIV transmission dynamics. The model considers both TB and acquired immune deficiency syndrome (AIDS) treatment for individuals with only one of the infectious diseases or both.
arxiv +1 more source
Biology of Blood and Marrow Transplantation, 2009 High-dose chemotherapy and autologous stem cell transplantation (SCT) or allogeneic SCT can lead to durable remissions in patients with hematologic malignancies. In the mid-1980s the first studies demonstrating the use of peripheral blood stem cells (PBSC) for autologous transplantation instead of bone marrow (BM) were performed.
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Cell, 1995 The three reviews that follow this introduction reflect contemporary knowledge of human immunodeficiency virus (HIV) infection and disease induction. Let us take a step back and reflect on why this virus infection, against which 10% of the budget of the National Institutes of Health is deployed, remains so enigmatic. ; © 1995 by Cell Press.
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Mathematical modelling of the first HIV/ZIKV co-infection cases in Colombia and Brazil [PDF]
arXiv, 2023 This paper presents a mathematical model to investigate co-infection with HIV/AIDS and zika virus (ZIKV) in Colombia and Brazil, where the first cases were reported in 2015-2016. The model considers the sexual transmission dynamics of both viruses and vector-host interactions.
arxiv
Bifurcation analysis of an age structured HIV infection model with both virus-to-cell and cell-to-cell transmissions [PDF]
, 2017 We make a mathematical analysis of an age structured HIV infection model with both virus-to-cell and cell-to-cell transmissions to understand the dynamical behavior of HIV infection in vivo. In the model, we consider the proliferation of uninfected CD4+ T cells by a logistic function and the infected CD4+ T cells are assumed to have an infection-age ...
arxiv +1 more source
Quantifying the recency of HIV infection using multiple longitudinal biomarkers [PDF]
arXiv, 2017 Knowledge of the time at which an HIV-infected individual seroconverts, when the immune system starts responding to HIV infection, plays a vital role in the design and implementation of interventions to reduce the impact of the HIV epidemic. A number of biomarkers have been developed to distinguish between recent and long-term HIV infection, based on ...
arxiv
HIV, TB and ART: the CD4 enigma [PDF]
arXiv, 2012 The concentration of CD4 T-lymphocytes (CD4 count), in a person's plasma is widely used to decide when to start HIV-positive people on anti-retroviral therapy (ART) and to predict the impact of ART on the future course of HIV and tuberculosis (TB). However, CD4 cell-counts vary widely within and among populations and depend on many factors besides HIV ...
arxiv
The pathology of HIV infection
Leprosy Review, 2002 The acquired immunodeficiency syndrome (AIDS) is the result of a human immunodeficiency virus (HIV) infection damaging the cell-mediated immune system. A wide range of opportunistic infections (OI) and tumours develop; additionally, HIV directly damages some organs.
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HIV infection and seizures [PDF]
Postgraduate Medical Journal, 1999 Summary New-onset seizures are frequent manifestations of central nervous system disorders in patients infected with human immunodeficiency virus (HIV). Seizures are more common in advanced stages of the disease, although they may occur early in the course of illness.
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The Coalescence of Intrahost HIV Lineages Under Symmetric CTL Attack [PDF]
arXiv, 2011 Cytotoxic T lymphocytes (CTLs) are immune system cells that are thought to play an important role in controlling HIV infection. We develop a stochastic ODE model of HIV-CTL interaction that extends current deterministic ODE models. Based on this stochastic model, we consider the effect of CTL attack on intrahost HIV lineages assuming CTLs attack ...
arxiv