Results 41 to 50 of about 476,743 (314)

What do primary care staff know and do about blood borne virus testing and care for migrant patients? A national survey

BMC Public Health, 2021
Background UK migrants born in intermediate to high prevalence areas for blood borne viruses (BBV) including hepatitis B, hepatitis C and HIV are at increased risk of these infections.
Rachel Roche, Ruth Simmons, Alison F. Crawshaw, Pip Fisher, Manish Pareek, Will Morton, Theresa Shryane, Kristina Poole, Arpana Verma, Ines Campos-Matos, Sema Mandal   +10 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Resurgence of HIV infection among men who have sex with men in Switzerland : mathematical modelling study [PDF]

, 2012
New HIV infections in men who have sex with men (MSM) have increased in Switzerland since 2000 despite combination antiretroviral therapy (cART). The objectives of this mathematical modelling study were: to describe the dynamics of the HIV epidemic in ...
Steven Derendinger (134735), Swiss HIV, Cohort Study, Glass, T. R., Fraser, C., Steven Derendinger, Christophe Fraser (7754), Vernazza, P., Frank de Wolf, Ard van Sighem (134719), Beatriz Vidondo (134721), Martin Gebhardt, Swiss HIV Cohort Study, Beatriz Vidondo, de Wolf Frank, Derendinger Steven, van Sighem, Ard, Jeannin André, Vernazza Pietro, Heiner C Bucher, Low, N., Martin Gebhardt (134732), Nicola Low (62560), Vidondo, B., Derendinger, Steven, Pietro Vernazza (82546), De Wolf, F., Bucher, Heiner C., Bezemer, D., Tracy R. Glass (134725), Bezemer, Daniela, Jeannin, André, Gebhardt, Martin, Bucher Heiner C., Tracy R Glass, de Wolf, Frank, Vidondo, Beatriz, Heiner C. Bucher (134728), Christophe Fraser, Jeannin, A., Daniela Bezemer, Gebhardt Martin, Bezemer Daniela, Bucher, H. C., Glass, Tracy R., Pietro Vernazza, Low Nicola, van Sighem Ard, André Jeannin, Daniela Bezemer (134739), Nicola Low, Glass Tracy R., Fraser, Christophe, Derendinger, S., Vidondo Beatriz, Ard van Sighem, Gebhardt, M., André Jeannin (134737), Frank de Wolf (89583), Fraser Christophe, Vernazza, Pietro, Low, Nicola, Van Sighem, A.   +61 more
core   +1 more source

Strong associations between national prevalence of various STIs suggests sexual network connectivity is a common underpinning risk factor

BMC Infectious Diseases, 2017
Background If national peak Human Immunodeficiency Virus (HIV) prevalence is positively associated with the prevalence of other sexually transmitted infections (STIs) from before or early on in the HIV epidemics this would suggest common underlying ...
Chris Kenyon
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Population-Level Benefits from Providing Effective HIV Prevention Means to Pregnant Women in High Prevalence Settings [PDF]

, 2013
Background:HIV prevalence among pregnant women in Southern Africa is extremely high. Epidemiological studies suggest that pregnancy increases the risk of HIV sexual acquisition and that HIV infections acquired during pregnancy carry higher risk of mother-
Dimitrov Dobromir, Brown Elizabeth R., Beigi Richard, Beigi, Richard, Brown, ER, Marrazzo, J, Elizabeth R Brown, Dimitrov, Dobromir, Boily, M-C, Elizabeth R. Brown (299789), Marie-Claude Boily (114790), Boily, MC, Marie-Claude Boily, Richard Beigi, Richard Beigi (459274), Boily Marie-Claude, Boily, Marie-Claude, Thorne, Claire, Dobromir Dimitrov, Dimitrov, D, Jeannie Marrazzo (459273), Marrazzo Jeannie, Jeannie Marrazzo, Brown, Elizabeth R., Beigi, R, Dobromir Dimitrov (459272), Marrazzo, Jeannie   +26 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Correlates of HIV-1 genital shedding in Tanzanian women. [PDF]

, 2011
BACKGROUND: Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who ...
Clare Tanton, David A. Ross, Watson-Jones Deborah, Weiss, Helen A, Watson-Jones, Deborah, Helen A Weiss, Richard J. Hayes, Laurent Belec, Tanton, Clare, Le Goff, Jerome, Hayes, Richard J, Deborah Watson-Jones, Le Goff Jerome, Belec Laurent, Baisley, Kathy, Changalucha John, Weiss Helen A., Everett Dean, Ross, David A, Everett, Dean, David A Ross, Kathy Baisley, Changalucha, John, Mary Rusizoka, Jerome Le Goff, Helen A. Weiss, John Changalucha, Tanton Clare, Dean Everett, Richard J Hayes, Baisley Kathy, Ross David A., Rusizoka, Mary, Rusizoka Mary, Hayes Richard J., Belec, Laurent   +35 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Challenges of Continuum of HIV/AIDS Care and Treatment in Tanzania: The Effects of Parasites Co-Infections, HIV Clinical Manifestations, and Adherence to Antiretroviral Therapy [PDF]

, 2012
In Tanzania, the National AIDS Control Program with the support of Non-Government Organizations is scaling-up Antiretroviral Therapy (ART) services to peripheral (rural) health facilities.
Idindili, Boniphace
core   +1 more source