Results 61 to 70 of about 1,835,308 (309)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Changes in risk behaviours and prevalence of sexually transmitted infections following HIV preventive interventions among female sex workers in five districts in Karnataka state, south India. [PDF]

, 2010
OBJECTIVES: To examine the impact of a large-scale HIV prevention programme for female sex workers (FSW) in Karnataka state, south India, on the prevalence of HIV/sexually transmitted infections (STI), condom use and programme coverage. METHODS: Baseline
Ramesh, B M, Jagannathan, Latta, Shajy, Isac, Beattie, Tara S H, Blanchard, James F, Beattie, Tara SH, Moses, Stephen, Washington, Reynold, Reza-Paul, Sushena, Ramesh, BM   +9 more
core   +1 more source

Reproductive tract infections: prevalence and risk factors in rural Bangladesh. [PDF]

, 2002
OBJECTIVE: To determine the prevalence of and risk factors for reproductive tract infections among men and women in a rural community in Bangladesh. METHODS: In the Matlab area a systematic sample of married non-pregnant women aged 15-50 years was drawn ...
Hawkes, Sarah, Islam, Shamim Sufia, Mabey, David, Morison, Linda, Ahmed, Farid, Alam, Nazmul, Gausia, Kaniz, Brown, David, Chakraborty, Jyotsnamoy   +8 more
core   +2 more sources

Fungal Infections in HIV-Infected Patients

Nippon Ishinkin Gakkai Zasshi, 2006
Recent situation of HIV-related mycosis was discussed in this paper, with the analysis of 1) annual report of HIV trends in Japan by the AIDS epidemiology committee, 2) report of HIV-related opportunistic infections (OIs) collected by the AIDS-OIs research group funded by the Ministry of Health, Labour and Welfare, and 3) 17 cases of HIV-related ...
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The Prevalence of HIV by Ethnic Group Is Correlated with HSV-2 and Syphilis Prevalence in Kenya, South Africa, the United Kingdom, and the United States

Interdisciplinary Perspectives on Infectious Diseases, 2014
Background. This paper investigates two issues: do ethnic/racial groups with high HIV prevalences also have higher prevalences of other STIs? and is HIV prevalence by ethnic group correlated with the prevalence of circumcision, concurrency, or having ...
Chris Richard Kenyon, Kara Osbak, Jozefien Buyze   +2 more
doaj   +1 more source

Cost-effectiveness of dual maternal HIV and syphilis testing strategies in high and low HIV prevalence countries: a modelling study

The Lancet Global Health, 2021
Summary: Background: Dual HIV and syphilis testing might help to prevent mother-to-child transmission (MTCT) of HIV and syphilis through increased case detection and treatment.
Patricia J Rodriguez, MPH, D Allen Roberts, MPH, Julianne Meisner, BVM&S, Monisha Sharma, PhD, Morkor Newman Owiredu, MBChB, Bertha Gomez, MD, Maeve B Mello, PhD, Alexey Bobrik, MD, Arkadii Vodianyk, MD, Andrew Storey, MBA, George Githuka, MBChB, Thato Chidarikire, PhD, Ruanne Barnabas, DPhil, Magdalena Barr-Dichiara, MPH, Muhammad S Jamil, PhD, Rachel Baggaley, MBBS, Cheryl Johnson, MA, Melanie M Taylor, MD, Alison L Drake, PhD   +18 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Syphilis in pregnant women living with HIV/AIDS in Brazil and the relationship between coinfection and mother-to-child transmission of HIV

BMC Public Health
Background HIV and syphilis are sexually transmitted infections of concern during pregnancy that affect women and children globally. However, limited data is available regarding the prevalence of syphilis infection among pregnant women living with HIV ...
Mayra Gonçalves Aragón, Leonor Henriette de Lannoy, Pâmela Cristina Gaspar, Ana Paula Betaressi da Silva, Ronaldo de Almeida Coelho, Draurio Barreira, Angélica Espinosa Miranda   +6 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source