Results 21 to 30 of about 2,187,766 (310)

HIV testing during pregnancy among women with a recent live birth—Seven US States, 2016–2019

Women's Health, 2023
Background: Although the United States has made progress in reducing the transmission of HIV from mother-to-child, it has not yet met the goal of reducing such transmissions to 70%. Self-reported HIV testing varied by state of residence.
Ndidi Nwangwu-Ike, Martha Kapaya, Keydra Oladapo, Denise V DAngelo   +3 more
doaj   +1 more source

Human immunodeficiency virus is a driven factor of human papilloma virus among women: evidence from a cross-sectional analysis in Yaoundé, Cameroon

Virology Journal, 2020
Background Human papillomavirus (HPV) is the leading cause of cervical cancers, causing 270.000 deaths annually worldwide of which 85% occur in developing countries with an increasing risk associated to HIV infection.
Samuel Martin Sosso, Michel Carlos Tommo Tchouaket, Joseph Fokam, Rachel Kamgaing Simo, Judith Torimiro, Aline Tiga, Elise Elong Lobe, Georgia Ambada, Achille Nange, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Valère Tala, Collins Chenwi, Aissatou Abba, Aude Christelle Ka’e, Bouba Yagai, Vittorio Colizzi, Alexis Ndjolo   +17 more
doaj   +1 more source

Evaluating the effect of the plan of national syphilis control in controlling the syphilis epidemic in Jiangsu, China 2010–2020

Frontiers in Public Health, 2023
BackgroundStarting in 2010, the Chinese government initiated a 10-year syphilis control plan, called the national syphilis control plan (NSCP), to address the emerging threat of syphilis.
Lingen Shi, Lingen Shi, Liping Chen, Xiaoyan Liu, Haiyang Hu, Yuheng Chen, Yunting Chen, Zhi Zhang, Ying Zhou, Jing Lu, Dandan Yang, Wenhui Guan   +11 more
doaj   +1 more source

SHIV remission in macaques with early treatment initiation and ultra long-lasting antiviral activity

Nature Communications
Studies in SIV-infected macaques show that the virus reservoir is particularly refractory to conventional suppressive antiretroviral therapy (ART). We posit that optimized ART regimens designed to have robust penetration in tissue reservoirs and long ...
Michele B. Daly, Chuong Dinh, Angela Holder, Donna Rudolph, Susan Ruone, Alison Swaims-Kohlmeier, George Khalil, Sunita Sharma, James Mitchell, Jillian Condrey, Daniel Kim, Yi Pan, Kelly Curtis, Peter Williams, William Spreen, Walid Heneine, J. Gerardo García-Lerma   +16 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Oral Islatravir in Macaques Decreases Lymphocytes and Monocytes and Is Associated with Immune Alterations

Pharmaceutics
Background: Islatravir (ISL) is a first-in-class nucleoside reverse transcriptase translocation inhibitor with high potency and long half-life in peripheral blood mononuclear cells (PBMCs). However, treatment and prevention of HIV with oral ISL in humans
Michele B. Daly, Daniel Kim, Seidu Inusah, Dawn Little, Jiyoung S. Kim, Natalia Makarova, Tiancheng E. Edwards, James Mitchell, Walid Heneine, Yi Pan, Charles W. Dobard, J. Gerardo García-Lerma   +11 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Preclinical evaluation of long-acting cabotegravir and rilpivirine for HIV post-exposure prophylaxis in a macaque modelResearch in context

EBioMedicine
Summary: Background: Current guidelines for post-exposure prophylaxis (PEP) recommend 28 days of daily oral antiretroviral drugs. However, low adherence and inadequate regimen completion represent important challenges.
Priya Srinivasan, Jining Zhang, Tiancheng Edwards, Chuong Dinh, Ayanna Green, Dawn Little, Tyana Singletary, Maria Mendoza, Yi Pan, Frank Deyounks, Ryan Johnson, Jonathan Lipscomb, Athena P. Kourtis, Walid Heneine, J. Gerardo García-Lerma, James M. Smith   +15 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source