Results 81 to 90 of about 3,269,718 (260)

Repeat HIV testing practices in the era of HIV self-testing among adults in KwaZulu-Natal, South Africa.

PLoS ONE, 2019
Repeat HIV testing is important in high HIV burden communities to enable sustainability of prevention initiatives; however, an understanding of repeat testing practices is limited.
Charlene Harichund, Pinky Kunene, Sinenhlanhla Simelane, Quarraisha Abdool Karim, Mosa Moshabela   +4 more
doaj   +1 more source

Understanding the Role of Reactions to Race-based Treatment on HIV Testing Behaviors [PDF]

, 2018
INTRODUCTION: In the United States, Blacks and Hispanics compared to Whites are disproportionately infected with HIV. Testing for HIV is critical to reduce HIV transmission, lower risk behaviors, and improve access to treatment among persons living with ...
Atere-Roberts, Joelle
core   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Asking God about the date you will die: HIV testing as a zone of uncertainty in rural Malawi [PDF]

Testing for HIV is becoming more available in Africa. Global advocates of testing see it as key to AIDS prevention. However, testing is not always perceived as a good thing by people at risk.
Susan Watkins, Amy Kaler
core  

Concurrent sexual partnerships and HIV prevalence in five urban communities of sub-Saharan Africa. [PDF]

, 2001
OBJECTIVE: To estimate parameters of concurrent sexual partnerships in five urban populations in sub-Saharan Africa and to assess their association with levels of HIV infection and other sexually transmitted infections (STI).
Lagarde, E., Ferry, B., N'Doye, I., Sukwa, T, Buvé, A, Laourou, M, Akam, E, Sukwa, T., Chege, J, N'Doye, I, Auvert, B, Maury, B, Morison, L., Caraël, M, Maury, E., Lagarde, E, Auvert, B., Chege, J., Buvé, A., Study Group on Heterogeneity of HIV Epidemics in African Cities, Caraël, M., Akam, E., Laourou, M., Ferry, B, Morison, L   +24 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Sexually Transmitted Infections among Adolescents in Greater Letaba, South Africa

Diversity
Adolescents remain highly vulnerable to sexually transmitted infections (STIs) due to behavioral, biological, and socio-cultural determinants, yet there is limited evidence from rural sub-Saharan Africa addressing the prevalence and gender-specific ...
Maite Leinett Thobakgale, Mathildah Mpata Mokgatle, Atholl Kleinhans, Muhammad Hoque   +3 more
doaj   +1 more source

Acceptability of HIV self-testing to support pre-exposure prophylaxis among female sex workers in Uganda and Zambia: results from two randomized controlled trials

BMC Infectious Diseases, 2018
Background HIV pre-exposure prophylaxis (PrEP) is highly effective for prevention of HIV acquisition, but requires HIV testing at regular intervals. Female sex workers (FSWs) are a priority population for HIV prevention interventions in many settings ...
Katrina F. Ortblad, Michael M. Chanda, Daniel Kibuuka Musoke, Thomson Ngabirano, Magdalene Mwale, Aidah Nakitende, Steven Chongo, Nyambe Kamungoma, Catherine Kanchele, Till Bärnighausen, Catherine E. Oldenburg   +10 more
doaj   +1 more source

Personal, interpersonal and structural challenges to accessing HIV testing, treatment and care services among female sex workers, men who have sex with men and transgenders in Karnataka state, South India. [PDF]

, 2012
BACKGROUND: Despite high HIV prevalence rates among most-at-risk groups, utilisation of HIV testing, treatment and care services was relatively low in Karnataka prior to 2008.
Suresh, M, Bhattacharjee, Parinita, Beattie, Tara SH, Moses, Stephen, Isac, Shajy, Ramesh, BM   +5 more
core   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

Advanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad, Anastasiia Steksova, Yuyang Tang, Leyao Huang, Alireza Velayati, Shengwei Zhang, Aditi Dey Poonam, Sina Jamalzadegan, Matthew Breen, Hongjie Chen, Mahsa Bagi, Guochun Jiang, Qingshan Wei   +12 more
wiley   +1 more source