Results 31 to 40 of about 638 (186)

Min–Max Dynamic Programming Control for Systems with Uncertain Mathematical Models via Differential Neural Network Bellman’s Function Approximation

open access: yesMathematics, 2023
This research focuses on designing a min–max robust control based on a neural dynamic programming approach using a class of continuous differential neural networks (DNNs). The proposed controller solves the robust optimization of a proposed cost function
Alexander Poznyak   +4 more
doaj   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

open access: yesAdvanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae   +27 more
wiley   +1 more source

HJB Equations and Stochastic Control on Half-Spaces of Hilbert Spaces

open access: yesJournal of Optimization Theory and Applications, 2023
AbstractIn this paper, we study a first extension of the theory of mild solutions for Hamilton–Jacobi–Bellman (HJB) equations in Hilbert spaces to the case where the domain is not the whole space. More precisely, we consider a half-space as domain, and a semilinear HJB equation.
Calvia A., Cappa G., Gozzi F., Priola E.
openaire   +3 more sources

Minute‐Scale Repeated Metabolic Probing of Living Cells Enabled by Rapid Parahydrogen‐Based Hyperpolarization

open access: yesAngewandte Chemie International Edition, EarlyView.
Rapid parahydrogen hyperpolarization combined with simple dilution enables biocompatible delivery of hyperpolarized pyruvate to immobilized living cells within ≈1 min. Repeated substrate injections reveal frequency‐dependent metabolic dynamics, introducing a new temporal dimension for hyperpolarized NMR studies of cellular metabolism and enabling rapid
Philipp R. Groß   +17 more
wiley   +1 more source

HJB-POD Feedback Control for Navier-Stokes Equations [PDF]

open access: yes, 2016
In this report we present the approximation of an infinite horizon optimal control problem for the evolutive Navier-Stokes system. The method is based on a model reduction technique, using a POD approximation, coupled with a Hamilton-Jacobi equation which characterizes the value function of the corresponding control problem for the reduced system ...
Alla, Alessandro, Hinze, Michael
openaire   +2 more sources

Stochastic Optimal Control of Averaged SDDE with Semi-Markov Switching and with Application in Economics

open access: yesMathematics
This paper is devoted to the study of stochastic optimal control of averaged stochastic differential delay equations (SDDEs) with semi-Markov switchings and their applications in economics.
Mariya Svishchuk, Anatoliy V. Swishchuk
doaj   +1 more source

Optimal Reinsurance-Investment Problem under Mean-Variance Criterion with n Risky Assets

open access: yesDiscrete Dynamics in Nature and Society, 2020
Based on the mean-variance criterion, this paper investigates the continuous-time reinsurance and investment problem. The insurer’s surplus process is assumed to follow Cramér–Lundberg model.
Peng Yang
doaj   +1 more source

Comparative Study of Gas and Liquid Flow in Packed Beds Using Phase‐Contrast MRI

open access: yesChemie Ingenieur Technik, EarlyView.
This work presents applications of phase‐contrast magnetic resonance imaging (MRI) to investigate fluid flow fields and temperature in packed beds. Comparison of ethane (C2H6) gas flow with that of water flow is done at similar flow conditions. The temperature of water is also measured using MRI.
Maitreyi Sangal   +4 more
wiley   +1 more source

Online Optimal Control of Robotic Systems with Single Critic NN-Based Reinforcement Learning

open access: yesComplexity, 2021
This paper suggests an online solution for the optimal tracking control of robotic systems based on a single critic neural network (NN)-based reinforcement learning (RL) method.
Xiaoyi Long, Zheng He, Zhongyuan Wang
doaj   +1 more source

Functional tooth unit, periodontal status, and association with weight change in older adults

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Literature reports that having fewer teeth is associated with reduced chewing capacity, which in turn may lead to weight changes due to diminished oral functionality. This study aims to assess the association between functional tooth units (FTU) and periodontal status and weight change among older adults participating in the Health,
Mariana S. Muñoz   +6 more
wiley   +1 more source

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