Results 21 to 30 of about 730,257 (221)
Epidemiology and immunogenetic background of islet cell antibody - positive nondiabetic schoolchildren : Ulm-Frankfurt population study [PDF]
, 1991 Islet cell antibodies (ICAs) were determined in a large cohort of white nondiabetic schoolchildren (n = 4287) from a homogenous population in southern Germany.
Glück, Michael +9 more
core +1 more source
Killer cell immunoglobulin-like receptors and their ligands : assessment of potential diagnostic and immunotherapeutic value [PDF]
, 2014 Human natural killer (NK) cells constitute an important arm of the innate immune system, which participates in protection against viral infections and elimination of malignant diseases.
Czaja, Karol Gustaw
core +1 more source
Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]
, 1992 The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef +7 more
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
, 2022 OBJECTIVES: Though Human Leukocyte Antigen (HLA) matching benefits are demonstrated in renal transplantation, evidence in heart transplantation is lacking, and its clinical feasibility is uncertain.
Poncelet, Alain +6 more
core +1 more source
Analyse the risk factors for producing anti-HLA antibodies in patients with hematological diseases
Zhongguo shuxue zazhiObjective To explore the risk factors for the production of anti-HLA antibodies in patients with hematological diseases before hematopoietic stemcell transplantation.
Kai JI +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Frequency of HLA antibodies in South India [PDF]
, 1993 Sera from 4088 pregnant women (649 antenatal bleeding and 3439 post-partum bleeding) living in Madurai, were collected and screened for anti-HLA. A, B and DR antibodies. 696 of them were screened for anti-HLA DR antibodies.
Mahendran, V. +10 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr +15 more
wiley +1 more source