Results 161 to 170 of about 282,112 (262)

Orthanq: transparent and uncertainty-aware haplotype quantification with application in HLA-typing. [PDF]

BMC Bioinformatics
Uzuner H, Paschen A, Schadendorf D, Köster J.   +3 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Advancements in HLA Typing Techniques and Their Impact on Transplantation Medicine. [PDF]

Med Princ Pract
Geo JA, Ameen R, Al Shemmari S, Thomas J.   +3 more
europepmc   +1 more source

arcasHLA: high-resolution HLA typing from RNAseq. [PDF]

Bioinformatics, 2020
Orenbuch R, Filip I, Comito D, Shaman J, Pe'er I, Rabadan R.   +5 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

The Importance of Confirming False Homozygosity in Pretransplant HLA Typing Results of Patients with Hematologic Malignancies. [PDF]

Int J Med Sci
Lee MY, You E.
europepmc   +1 more source

Early Chidamide Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation in High‐Risk Myeloid Malignancies: A Prospective Cohort With Time‐Dependent External‐Control Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Chidamide is an oral histone deacetylase inhibitor whose use as early maintenance after allogeneic hematopoietic stem cell transplantation (HSCT) remains insufficiently defined. This prospective single‐center Phase 1/2 cohort included all 47 patients enrolled and treated by March 31, 2026.
Haonan Yang, Qiushi Liang, Zhigang Liu, Xinchuan Chen, Pu Kuang, Tian Dong, Ting Liu, Ting Niu, Yuhuan Zheng, Jie Ji   +9 more
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Associations Between Clinical Manifestations of SARS-CoV-2 Infection and HLA Alleles in a Caucasian Population: A Molecular HLA Typing Study. [PDF]

J Clin Med
Tymoniuk B, Borowiec M, Makowska J, Holwek E, Sarnik J, Styrzyński F, Dróżdż I, Lewiński A, Stasiak M.   +8 more
europepmc   +1 more source

Performance of a multiplexed amplicon-based next-generation sequencing assay for HLA typing. [PDF]

PLoS One, 2020
Liu C, Duffy BF, Weimer ET, Montgomery MC, Jennemann JE, Hill R, Phelan D, Lay L, Parikh BA.   +8 more
europepmc   +1 more source