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Deceased organ donation: laboratory testing and histocompatibility assessment in Korea [PDF]

Clinical Transplantation and Research
Histocompatibility testing is essential for ensuring both safety and fairness in deceased donor organ transplantation. In Korea, such testing is strictly regulated under the Organ Transplant Act and centralized within organ procurement organization ...
Borae G. Park, Samuel Lee
doaj   +3 more sources

Histocompatibility Testing for Organ Transplantation Purposes in Albania: A Single Center Experience [PDF]

Balkan Medical Journal, 2014
Background: Histocompatibility testing (HT) which includes donor-recipient human leukocyte antigen (HLA) matching, cross-match testing (XMT) and anti-HLA antibody searching are crucial examinations in solid organ transplantation aiming to avoid the ...
Erkena Shyti, Genc Sulcebe, Alma Idrizi
doaj   +3 more sources

Status quo of histocompatibility testing and prospects for virtual crossmatching within the Korean kidney allocation system: survey of laboratory directors [PDF]

Clinical Transplantation and Research
Background : The Korean kidney allocation system (KAS) currently imposes disparities for highly sensitized candidates because it does not account for human leukocyte antigen (HLA) antibody-defined unacceptable antigens.
John Jeongseok Yang, Borae G Park, Hyun-Woo Choi, Eun Young Song, Jaeseok Yang, Jae Berm Park, Eun-Suk Kang   +6 more
doaj   +3 more sources

Seventy-five years of service: an overview of the College of American Pathologists’ proficiency testing program in histocompatibility and identity testing [PDF]

Frontiers in Genetics, 2023
The Histocompatibility and Identity Testing Committee offers an overview of the College of American Pathologists’ (CAP) Proficiency Testing (PT) program, commemorating its significant 75th anniversary in 2024. The CAP PT program has undergone significant
H. Cliff Sullivan, Manish J. Gandhi, Sujata Gaitonde, Ramya Narasimhan, Ketevan Gendzekhadze, Soumya Pandey, Rhonda K. Roby, George C. Maha, Harmeet Kaur, Jennifer J. Schiller, Julie McDowell, Maria Smith, Chang Liu, Gerald P. Morris   +13 more
doaj   +2 more sources

Aspects of histocompatibility testing in xenotransplantation. [PDF]

Transpl Immunol, 2021
Xenotransplantation, using genetically-modified pigs for clinical organ transplantation, is a solution to the organ shortage. The biggest barrier to clinical implementation is the antigenicity of pig cells. Humans possess preformed antibody to pig cells that initiate antibody-mediated rejection of pig organs in primates. Advances in genetic engineering
Ladowski JM, Houp J, Hauptfeld-Dolejsek V, Javed M, Hara H, Cooper DKC.   +5 more
europepmc   +3 more sources

Histocompatibility Testing: A Fundamental Aspect of Renal Transplant Workup

Transplantology
Histocompatibility testing is pivotal in any renal transplantation workup, aimed at enhancing prospective donor recipient compatibility and improving transplant outcomes.
Vikash Chandra Mishra, Dinesh Chandra, Vimarsh Raina   +2 more
doaj   +2 more sources

External proficiency testing for histocompatibility and immunogenetics in today and future [PDF]

Frontiers in Genetics
The Histocompatibility and Immunogenetics laboratories provide disease association and pharmacogenetic analyses as well as the tests required for transplantation immunology and transfusion medicine.
Fatma Savran Oguz
doaj   +2 more sources

Current status and perspectives of the quality system in histocompatibility laboratories in Poland

Frontiers in Genetics
Allogeneic transplantation is a multi-step process involving many clinicians and laboratory personnel working together to achieve a common goal—to maximize the recipients’ chance of survival and to improve their quality of life.
Izabela Uhrynowska-Tyszkiewicz, Izabela Uhrynowska-Tyszkiewicz, Katarzyna Bogunia-Kubik, Monika Baj-Krzyworzeka, Monika Baj-Krzyworzeka, Barbara Piątosa, Barbara Piątosa   +6 more
doaj   +3 more sources

Identifying a Minor Histocompatibility Antigen in Mauritian Cynomolgus Macaques Encoded by APOBEC3C [PDF]

Frontiers in Immunology, 2020
Allogeneic hematopoietic stem cell transplants can lead to dramatic reductions in human immunodeficiency virus (HIV) reservoirs. This effect is partially mediated by donor T cells recognizing lymphocyte-expressed minor histocompatibility antigens (mHAgs).
Jason T. Weinfurter, Michael E. Graham, Adam J. Ericsen, Lea M. Matschke, Sian Llewellyn-Lacey, David A. Price, David A. Price, Roger W. Wiseman, Matthew R. Reynolds, Matthew R. Reynolds   +9 more
doaj   +2 more sources

Advancing precision in histocompatibility and immunogenetics: a comprehensive review of the UCLA exchange program [PDF]

Frontiers in Genetics
Precise typing of human leukocyte antigens (HLA) is crucial for clinical hematopoietic stem cell and solid organ transplantations, transfusion medicine, HLA-related disease association, and drug hypersensitivity analysis.
Qiuheng Zhang, Arlene F. Locke, Andrea Carolina Alvarez, Maria L. Cabarong, Lek Ching Liv, Belen Garcia P. Alfaro, David W. Gjertson, Elaine F. Reed   +7 more
doaj   +2 more sources