Results 21 to 30 of about 46,380 (292)

Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves, Griffin, D.K., Wesley C Warren, Edwards, Scott, Völker, Martin, Völker Martin, Westerdahl Helena, Burt, D.W., Graves, Tina, Griffin Darren K, Martin Völker, Burt, David W, Darren K Griffin, Helena Westerdahl, Godinez Ricardo, Edwards, S.V., Edwards, Scott V, Kotkiewicz, H., Ekblom, Robert,, Ekblom Robert, Warren, Wesley C, Warren, W.C., Ekblom, Robert, Robert Ekblom, David W Burt, Ricardo Godinez, Warren, Wesley C., Scott V Edwards, Lund University., Griffin, Darren K., Godinez, Ricardo, Westerdahl, Helena, Ekblom, R., Westerdahl, Helena,, Edwards, Scott V., Kotkiewicz, Holly, Voelker, Martin, Graves Tina, Christopher N Balakrishnan, Balakrishnan, Christopher N, Godinez, R., Warren Wesley C, Burt David W, Balakrishnan, Christopher N., Kotkiewicz Holly, Griffin, Darren K, Westerdahl, H., Balakrishnan Christopher N, Balakrishnan, C.N., Graves, T., Graves, Tina A., Burt, David W., Holly Kotkiewicz, Volker, M., Edwards Scott V   +54 more
core   +1 more source

A positive complement dependent cytotoxicity immunoglobulin G crossmatch due to auto-antibodies with a negative luminex bead assays in a renal transplant recipient: A Diagnostic dilemma

Asian Journal of Transfusion Science, 2018
Transplant recipients are always at a risk of developing anti-human leukocyte antigen (HLA) antibodies due to prior sensitizing events such as blood transfusions, multiple pregnancies, or transplantation.
Mohit Chowdhry, Raj Nath Makroo, Brinda Kakkar, Yogita Thakur, Manoj Kumar, Mandhata Singh   +5 more
doaj   +1 more source

Female rose bitterling prefer MHC-dissimilar males : experimental evidence [PDF]

, 2012
The role of genetic benefits in female mate choice remains a controversial aspect of sexual selection theory. In contrast to “good allele” models of sexual selection, “compatible allele” models of mate choice predict that females prefer mates with ...
Bryja, Pepa, Bryjova, Anna, Josef Bryja (150556), Smith, Carl, Spence, Rowena Grace Alison, Martin Reichard (150549), Martin Reichard, Rowena Spence, Rowena Spence (150551), Carl Smith, Anna Bryjová, Josef Bryja, Anna Bryjová (150553), Martin Reichard, Reichard, Martin, Carl Smith (150560)   +15 more
core   +1 more source

Major Histocompatibility Complex Binding, Eluted Ligands, and Immunogenicity: Benchmark Testing and Predictions

Frontiers in Immunology, 2020
Antidrug antibody (ADA) responses impact drug safety, potency, and efficacy. It is generally assumed that ADA responses are associated with human leukocyte antigen (HLA) class II-restricted CD4+ T-cell reactivity.
Sinu Paul, Alba Grifoni, Bjoern Peters, Bjoern Peters, Alessandro Sette, Alessandro Sette   +5 more
doaj   +1 more source

Successful Deceased Donor Kidney Transplantation in a Highly Sensitized Patient after Reclassification of Unacceptable Antigens Based on HLA Epitope Analysis

Revista Portuguesa de Nefrologia e Hipertensão, 2022
For patients with end stage renal disease, kidney transplant offers significant survival and quality-of-life advantages compared with dialysis. But for patients seeking transplant who are highly sensitized, waiting times have traditionally been long and
Daniela Alfere, Sandra Tafulo, Isabel Tavares, Ana Teresa Nunes, Ana Rocha, Manuela Bustorff, Susana Sampaio   +6 more
doaj   +1 more source

Novel alleles in the era of next-generation sequencing-based HLA typing calls for standardization and policy

Frontiers in Genetics, 2023
Next-Generation Sequencing (NGS) has transformed clinical histocompatibility laboratories through its capacity to provide accurate, high-throughput, high-resolution typing of Human Leukocyte Antigen (HLA) genes, which is critical for transplant safety ...
Jenny N. Tran, Karen R. Sherwood, Ahmed Mostafa, Rey Vincent Benedicto, Allaa ElaAlim, Anna Greenshields, Paul Keown, Robert Liwski, James H. Lan   +8 more
doaj   +1 more source

Discrepancies in HLA typing: use of different methods to confirm doubtful or inconclusive results

Acta Scientiarum. Health Sciences, 2014
http://dx.doi.org/10.4025/actascihealthsci.v36i1.15575 The major histocompatibility complex (MHC) is a set of genes found on the short arm of chromosome 6. MHC molecules in human beings are known as human leukocyte antigens (HLA). HLA polymorphism can be
Rejane Cristina Ribas-Silva, Adriana Danmvolf Ribas, Luciana Borges Giarola, Marina Raduy Botelho, Marco Antônio Braga, Sueli Donizete Borelli   +5 more
doaj   +1 more source

Definitions of histocompatibility typing terms [PDF]

, 2011
Histocompatibility testing for stem cell and solid organ transplantation has become increasingly complex as newly discovered HLA alleles are described.
Wagenknecht, Dawn R, Cynthia Taves, Carolyn Katovich Hurley, Fernandez-Vina, Marcelo, Heslop, Helen, Noreen, Harriet, Helen Heslop, Marcelo Fernandez-Vina, Eduardo Nunes, Dawn R. Wagenknecht, Sacchi, Nicoletta, Eisenbrey, A Bradley, Harriet Noreen, Kay Poulton, Nunes, Eduardo, Gottfried Fischer, Nicoletta Sacchi, Taves, Cynthia, Fischer, Gottfried, Hurley, Carolyn Katovich, Wacker, Kara, Kara Wacker, Poulton, Kay, A. Bradley Eisenbrey   +23 more
core   +1 more source

Desensitization using IVIG alone for living-donor kidney transplant: impact on donor-specific antibodies

Brazilian Journal of Nephrology, 2022
Introduction: Sensitization to human leukocyte antigen is a barrier to. Few data have been published on desensitization using polyvalent human intravenous immunoglobulin (IVIG) alone.
Luiz Roberto de Sousa Ulisses, Jenaine Oliveira Paixão, Fabiana Agena, Patrícia Soares de Souza, Flávio J Paula, Gislene Bezerra, Hélcio Rodrigues, Nicolas Panajotopolous, Elias David-Neto, Maria Cristina Ribeiro de Castro   +9 more
doaj   +2 more sources

Frecuencias alélicas, genotípicas y haplotípicas HLA-A, HLA-B, HLA-DRB1 en donantes fallecidos, Medellín, Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La caracterización genética del sistema HLA es de gran utilidad en estudios antropogenéticos, en la comprensión de mecanismos asociados a susceptibilidad o resistencia a diversas enfermedades, en los fenómenos inmunológicos durante el ...
Libia M. Rodríguez, Mabel C. Giraldo, Natalia García, Laura Velásquez, Sara C. París, Cristiam M. Álvarez, Luis F. García   +6 more
doaj   +1 more source