Results 21 to 30 of about 2,551,465 (297)
Frontiers in Genetics, 2023 Next-Generation Sequencing (NGS) has transformed clinical histocompatibility laboratories through its capacity to provide accurate, high-throughput, high-resolution typing of Human Leukocyte Antigen (HLA) genes, which is critical for transplant safety ...
Jenny N. Tran +8 more
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Discrepancies in HLA typing: use of different methods to confirm doubtful or inconclusive results
Acta Scientiarum. Health Sciences, 2014 http://dx.doi.org/10.4025/actascihealthsci.v36i1.15575 The major histocompatibility complex (MHC) is a set of genes found on the short arm of chromosome 6. MHC molecules in human beings are known as human leukocyte antigens (HLA). HLA polymorphism can be
Rejane Cristina Ribas-Silva +5 more
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Brazilian Journal of Nephrology, 2022 Introduction: Sensitization to human leukocyte antigen is a barrier to. Few data have been published on desensitization using polyvalent human intravenous immunoglobulin (IVIG) alone.
Luiz Roberto de Sousa Ulisses +9 more
doaj +2 more sources
Biomédica: revista del Instituto Nacional de Salud, 2007 Introducción. La caracterización genética del sistema HLA es de gran utilidad en estudios antropogenéticos, en la comprensión de mecanismos asociados a susceptibilidad o resistencia a diversas enfermedades, en los fenómenos inmunológicos durante el ...
Libia M. Rodríguez +6 more
doaj +1 more source
Quality Control in Histocompatibility Testing: Current Standards, Challenges, and Future Directions
Indian Journal of TransplantationHistocompatibility testing is pivotal to the transplantation process since it helps determine immune compatibility between donors and recipients. This compatibility reduces the risk of rejection and improves transplant outcomes.
Vikash Chandra Mishra +2 more
doaj +1 more source
Downregulation of major histocompatibility complex class I in bovine papillomas [PDF]
, 2004 Bovine papillomavirus (BPV) induces papillomas in cattle; in the great majority of cases, these regress due to the host immune response, but they can persist and progress to malignancy.
Marchetti, B +6 more
core +1 more source
Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]
, 1997 Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Pieters, J. +11 more
core +1 more source
Current status and perspectives of the quality system in histocompatibility laboratories in Poland
Frontiers in GeneticsAllogeneic transplantation is a multi-step process involving many clinicians and laboratory personnel working together to achieve a common goal—to maximize the recipients’ chance of survival and to improve their quality of life.
Izabela Uhrynowska-Tyszkiewicz +6 more
doaj +1 more source
Identifying a Minor Histocompatibility Antigen in Mauritian Cynomolgus Macaques Encoded by APOBEC3C
Frontiers in Immunology, 2020 Allogeneic hematopoietic stem cell transplants can lead to dramatic reductions in human immunodeficiency virus (HIV) reservoirs. This effect is partially mediated by donor T cells recognizing lymphocyte-expressed minor histocompatibility antigens (mHAgs).
Jason T. Weinfurter +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source