Results 21 to 30 of about 46,167 (292)

Successful Deceased Donor Kidney Transplantation in a Highly Sensitized Patient after Reclassification of Unacceptable Antigens Based on HLA Epitope Analysis

Revista Portuguesa de Nefrologia e Hipertensão, 2022
For patients with end stage renal disease, kidney transplant offers significant survival and quality-of-life advantages compared with dialysis. But for patients seeking transplant who are highly sensitized, waiting times have traditionally been long and
Daniela Alfere, Sandra Tafulo, Isabel Tavares, Ana Teresa Nunes, Ana Rocha, Manuela Bustorff, Susana Sampaio   +6 more
doaj   +1 more source

Technics of Histocompatibility Testing

New England Journal of Medicine, 1970
core   +5 more sources

Major Histocompatibility Complex Binding, Eluted Ligands, and Immunogenicity: Benchmark Testing and Predictions

Frontiers in Immunology, 2020
Antidrug antibody (ADA) responses impact drug safety, potency, and efficacy. It is generally assumed that ADA responses are associated with human leukocyte antigen (HLA) class II-restricted CD4+ T-cell reactivity.
Sinu Paul, Alba Grifoni, Bjoern Peters, Bjoern Peters, Alessandro Sette, Alessandro Sette   +5 more
doaj   +1 more source

Novel alleles in the era of next-generation sequencing-based HLA typing calls for standardization and policy

Frontiers in Genetics, 2023
Next-Generation Sequencing (NGS) has transformed clinical histocompatibility laboratories through its capacity to provide accurate, high-throughput, high-resolution typing of Human Leukocyte Antigen (HLA) genes, which is critical for transplant safety ...
Jenny N. Tran, Karen R. Sherwood, Ahmed Mostafa, Rey Vincent Benedicto, Allaa ElaAlim, Anna Greenshields, Paul Keown, Robert Liwski, James H. Lan   +8 more
doaj   +1 more source

Discrepancies in HLA typing: use of different methods to confirm doubtful or inconclusive results

Acta Scientiarum. Health Sciences, 2014
http://dx.doi.org/10.4025/actascihealthsci.v36i1.15575 The major histocompatibility complex (MHC) is a set of genes found on the short arm of chromosome 6. MHC molecules in human beings are known as human leukocyte antigens (HLA). HLA polymorphism can be
Rejane Cristina Ribas-Silva, Adriana Danmvolf Ribas, Luciana Borges Giarola, Marina Raduy Botelho, Marco Antônio Braga, Sueli Donizete Borelli   +5 more
doaj   +1 more source

Desensitization using IVIG alone for living-donor kidney transplant: impact on donor-specific antibodies

Brazilian Journal of Nephrology, 2022
Introduction: Sensitization to human leukocyte antigen is a barrier to. Few data have been published on desensitization using polyvalent human intravenous immunoglobulin (IVIG) alone.
Luiz Roberto de Sousa Ulisses, Jenaine Oliveira Paixão, Fabiana Agena, Patrícia Soares de Souza, Flávio J Paula, Gislene Bezerra, Hélcio Rodrigues, Nicolas Panajotopolous, Elias David-Neto, Maria Cristina Ribeiro de Castro   +9 more
doaj   +2 more sources

Frecuencias alélicas, genotípicas y haplotípicas HLA-A, HLA-B, HLA-DRB1 en donantes fallecidos, Medellín, Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La caracterización genética del sistema HLA es de gran utilidad en estudios antropogenéticos, en la comprensión de mecanismos asociados a susceptibilidad o resistencia a diversas enfermedades, en los fenómenos inmunológicos durante el ...
Libia M. Rodríguez, Mabel C. Giraldo, Natalia García, Laura Velásquez, Sara C. París, Cristiam M. Álvarez, Luis F. García   +6 more
doaj   +1 more source

Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus).

, 2009
(c) 2009 Teacher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Trenton W J Garner, Richard A. Nichols, Trenton W. J. Garner, Garner, TWJ, Teacher, AGF, Amber G F Teacher, Teacher Amber G. F., Richard A Nichols, Garner Trenton W. J., Amber G. F. Teacher, Nichols, RA, Nichols Richard A.   +11 more
core   +1 more source

Quality Control in Histocompatibility Testing: Current Standards, Challenges, and Future Directions

Indian Journal of Transplantation
Histocompatibility testing is pivotal to the transplantation process since it helps determine immune compatibility between donors and recipients. This compatibility reduces the risk of rejection and improves transplant outcomes.
Vikash Chandra Mishra, Dinesh Chandra, Vimarsh Raina   +2 more
doaj   +1 more source

Definitions of histocompatibility typing terms: Harmonization of Histocompatibility Typing Terms Working Group

, 2011
Histocompatibility testing for stem cell and solid organ transplantation has become increasingly complex as newly discovered human leukocyte antigen (HLA) alleles are described.
Cynthia Taves, Eisenbrey, A. Bradley, Carolyn Katovich Hurley, Fernandez-Vina, Marcelo, Heslop, Helen, Noreen, Harriet, Helen Heslop, Marcelo Fernandez-Vina, Eduardo Nunes, Dawn R. Wagenknecht, Sacchi, Nicoletta, Harriet Noreen, Kay Poulton, Nunes, Eduardo, Gottfried Fischer, Nicoletta Sacchi, Taves, Cynthia, Fischer, Gottfried, Hurley, Carolyn Katovich, Wacker, Kara, Kara Wacker, Poulton, Kay, A. Bradley Eisenbrey, Wagenknecht, Dawn R.   +23 more
core   +1 more source