Results 41 to 50 of about 83,183 (296)

Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies [PDF]

, 2008
The E3/19K protein of human adenovirus type 2 (Ad2) was the first viral protein shown to interfere with antigen presentation. This 25 kDa transmembrane glycoprotein binds to major histocompatibility complex (MHC) class I molecules in the endoplasmic ...
Ahmed, Altschul, Andersson, Beatrice Menz, Beier, Bennett, Bruder, Bryson, Burgert, Burgert, Burgert, Burgert, Burgert, Cole, Cox, Deryckere, Edgar, Elsing, Feuerbach, Flomenberg, Flomenberg, Fox, Gabathuler, Gewurz, Ginsberg, Hans-Gerhard Burgert, Hermiston, Hilgendorf, Jackson, Jackson, Jefferies, Katja Koebernick, Kornfeld, Krogh, Kurowski, Köhler, Körner, Lichtenstein, Liu, Liu, Lodoen, Mans, Martina Sester, McNees, McSharry, Nilsson, Persson, Pääbo, Pääbo, Pääbo, Ralf Schmid, Rawle, Rost, Rost, Rost, Sester, Sester, Tanaka, The_UniProt_Consortium, von Herrath, Windheim, Wold, Wold   +62 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Mechanism of remodeling and local effects in vivo of a new injectable cosmetic filler

Scientific Reports, 2023
By studying the local effects of a new type of injectable cosmetic filler implanted into the animal to explore the mechanism of remodeling and cosmetic effect of this kind of product.
Likui Sun, Xiaoxia Sun, Wenting Ruan, Guoxi Che, Fuyu Zhu, Chenghu Liu, Min Wan   +6 more
doaj   +1 more source

Prozone phenomenon in pretransplant testing: An interesting conundrum involving solid-phase and cell-based assays

Asian Journal of Transfusion Science, 2022
BACKGROUND: Human leukocyte antigen (HLA) is a major determinant in deciding upon solid organ histocompatibility. Donor-specific anti-HLA antibodies (Donor-specific anti-HLA antibodies (DSAs)) are always a contraindication for solid organ transplantation,
Parvind Singh, Aseem Kumar Tiwari, Vikash Chandra Mishra, Trupti Vimlakar Deshpande, Pranav Dorwal, Amit Kr Bhardwaj, Sneha Kumari, Vimarsh Raina   +7 more
doaj   +1 more source

Genetic Variation in the IL-6 and HLA-DQB1 Genes Is Associated with Spontaneous Clearance of Hepatitis C Virus Infection. [PDF]

, 2016
Background. Millions of people are infected with hepatitis C virus (HCV) worldwide and 30% spontaneously clear the infection. Reasons for HCV clearance without antiviral treatment are not well understood. Methods.
Belitskaya-Lévy, Ilana, Chary, Aarthi, Holodniy, Mark, Lazzeroni, Laura C, Monto, Alexander, Ryan, James, Waldron, Paul Ravi, Winters, Mark, Won, Johann   +8 more
core   +3 more sources

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

An Interesting Case of Renal Transplantation: Resolving Discrepancies in Histocompatibility Testing

Indian Journal of Transplantation
Histocompatibility testing plays an important role in the success of renal transplantation outcome by ensuring optimal donor recipient compatibility. Developments in testing methods have increased transplant success, but discrepancies between different ...
Vikash Chandra Mishra, Dinesh Chandra, Ritu Sharma, Vimarsh Raina   +3 more
doaj   +1 more source

Assessing the utilization of high-resolution 2-field HLA typing in solid organ transplantation. [PDF]

, 2019
HLA typing in solid organ transplantation (SOT) is necessary for determining HLA-matching status between donor-recipient pairs and assessing patients\u27 anti-HLA antibody profiles.
Dinh, Anh, Duke, Jamie L., Ferriola, Deborah, Frackelton, Edward C., Gasiewski, Allison, Geier, Steven S., Heron, Steven, Huang, Yanping, Kentzel, Ethan, Kneib, Carolina, Mehler, Hilary, Mignogno, Michael T., Monos, Dimitri, Morlen, Ryan, Mosbruger, Timothy, Slavich, Larissa, Timofeeva, Olga A.   +16 more
core   +1 more source