Results 41 to 50 of about 46,380 (292)

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

An Interesting Case of Renal Transplantation: Resolving Discrepancies in Histocompatibility Testing

Indian Journal of Transplantation
Histocompatibility testing plays an important role in the success of renal transplantation outcome by ensuring optimal donor recipient compatibility. Developments in testing methods have increased transplant success, but discrepancies between different ...
Vikash Chandra Mishra, Dinesh Chandra, Ritu Sharma, Vimarsh Raina   +3 more
doaj   +1 more source

Mechanism of remodeling and local effects in vivo of a new injectable cosmetic filler

Scientific Reports, 2023
By studying the local effects of a new type of injectable cosmetic filler implanted into the animal to explore the mechanism of remodeling and cosmetic effect of this kind of product.
Likui Sun, Xiaoxia Sun, Wenting Ruan, Guoxi Che, Fuyu Zhu, Chenghu Liu, Min Wan   +6 more
doaj   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Tipificación molecular de los antígenos leucocitarios humanos, Estado del arte y perspectivas para los transplantes de células madre en Costa Rica Molecular typing of Human Leukocyte Antigens, State-of-theart and Perspectives for Stem cell Transplantation in Costa Rica

Acta Médica Costarricense, 2010
El sistema de antígenos leucocitarios (Human Leukocyte Antigen) es el más polimórfico en el ser humano. Su función la realiza regulando la respuesta inmune mediante su unión a moléculas como el receptor de células T, participando en la presentación de ...
Esteban Arrieta-Bolaños, Lizbeth Salazar-Sánchez   +1 more
doaj  

Proficiency testing within Eurotransplant

Frontiers in Genetics
Eurotransplant is responsible for the international allocation of organs between eight countries in Europe. All HLA laboratories affiliated to Eurotransplant must be EFI or ASHI-accredited and must participate in the Eurotransplant external proficiency ...
Yvonne M. Zoet, Sebastiaan Heidt, Marissa J. H. van der Linden-van Oevelen, Geert W. Haasnoot, Frans H. J. Claas   +4 more
doaj   +1 more source

Histocompatibility testing in patients with carcinoma of the bladder [PDF]

Cancer, 1983
A number of disease states have been found to have a positive association with certain HLA antigens. Weak associations have been described for a number of cancers. Seventy patients with transitional cell carcinoma of the bladder underwent serotyping for HLA, A, B, C, and DR antigens. There were 54 men and 16 women patients with a mean age of 65.3 years.
B, Lytton, C, O'Toole, R, Tiptaft, H, Festenstein, J R, Batchelor   +4 more
openaire   +2 more sources

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

HLA-testing and laboratory medicine [PDF]

, 2013
Histocompatibility typing HLA-matching or compatibility is the major condition for standard allogeneic transplantation. HLA-testing is generally done on PB leukocytes or lymphocytes.
Kerry Atkinson, DiPaola, Nicholas R., Atkinson, Kerry, Munker, Reinhold, Nicholas R. DiPaola, Reinhold Munker   +5 more
core   +1 more source