Results 11 to 20 of about 83,183 (296)

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase [PDF]

open access: yes, 2020
Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs.
Bausenwein, Judith   +13 more
core   +2 more sources

HLA alleles in renal transplant recipients with nonmelanoma skin cancer in southeastern Brazil [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
: Background: Renal transplant recipients are submitted to immunosuppression to avoid graft rejection, which makes them susceptible to various conditions.
Clarissa Schmidt Rogel   +5 more
doaj   +1 more source

Murine liver allograft transplantation: Tolerance and donor cell chimerism [PDF]

open access: yes, 1994
Nonarterialized orthotopic liver transplantation with no immunosuppression was performed in 13 mouse‐strain combinations. Two strain combinations with major histocompatibility complex class I and class II and minor histocompatibility complex disparity ...
Arnold   +45 more
core   +1 more source

Historic landmarks in clinical transplantation: Conclusions from the consensus conference at the University of California, Los Angeles [PDF]

open access: yes, 2000
The transplantation of organs, cells, and tissues has burgeoned during the last quarter century, with the development of multiple new specialty fields.
Brent, LB   +11 more
core   +1 more source

Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia [PDF]

open access: yes, 2019
Introduction Chromosomal abnormalities are frequent events in hematological malignancies. The degree of HLA compatibility between donor and recipient in hematopoietic stem cell transplantation is critical.
Breman, Amy M.   +10 more
core   +1 more source

A positive complement dependent cytotoxicity immunoglobulin G crossmatch due to auto-antibodies with a negative luminex bead assays in a renal transplant recipient: A Diagnostic dilemma

open access: yesAsian Journal of Transfusion Science, 2018
Transplant recipients are always at a risk of developing anti-human leukocyte antigen (HLA) antibodies due to prior sensitizing events such as blood transfusions, multiple pregnancies, or transplantation.
Mohit Chowdhry   +5 more
doaj   +1 more source

Successful Deceased Donor Kidney Transplantation in a Highly Sensitized Patient after Reclassification of Unacceptable Antigens Based on HLA Epitope Analysis

open access: yesRevista Portuguesa de Nefrologia e Hipertensão, 2022
For patients with end stage renal disease, kidney transplant offers significant survival and quality-of-life advantages compared with dialysis. But for patients seeking transplant who are highly sensitized, waiting times have traditionally been long and
Daniela Alfere   +6 more
doaj   +1 more source

Major Histocompatibility Complex Binding, Eluted Ligands, and Immunogenicity: Benchmark Testing and Predictions

open access: yesFrontiers in Immunology, 2020
Antidrug antibody (ADA) responses impact drug safety, potency, and efficacy. It is generally assumed that ADA responses are associated with human leukocyte antigen (HLA) class II-restricted CD4+ T-cell reactivity.
Sinu Paul   +5 more
doaj   +1 more source

Novel alleles in the era of next-generation sequencing-based HLA typing calls for standardization and policy

open access: yesFrontiers in Genetics, 2023
Next-Generation Sequencing (NGS) has transformed clinical histocompatibility laboratories through its capacity to provide accurate, high-throughput, high-resolution typing of Human Leukocyte Antigen (HLA) genes, which is critical for transplant safety ...
Jenny N. Tran   +8 more
doaj   +1 more source

Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males [PDF]

open access: yes, 2013
Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus
Alcaide M   +8 more
core   +1 more source

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