Results 11 to 20 of about 282,112 (262)

HLA Typing for the Next Generation [PDF]

PLOS ONE, 2015
Allele-level resolution data at primary HLA typing is the ideal for most histocompatibility testing laboratories. Many high-throughput molecular HLA typing approaches are unable to determine the phase of observed DNA sequence polymorphisms, leading to ambiguous results.
Neema P Mayor, James Robinson, Alasdair J M McWhinnie, Swati Ranade, Kevin Eng, William Midwinter, Will P Bultitude, Chen-Shan Chin, Brett Bowman, Patrick Marks, Henny Braund, J Alejandro Madrigal, Katy Latham, Steven G E Marsh   +13 more
openaire   +5 more sources

consHLA: a next generation sequencing consensus-based HLA typing workflow. [PDF]

BMC Bioinformatics
Background Human Leukocyte Antigens (HLA) play central roles in histocompatibility and immune system functions, including antigen presentation. Accurate typing of Class I and II HLA genes is crucial for transplant tissue matching, characterising ...
Bowen-James R, Wu W, Wong-Erasmus M, Quinn JMW, Mayoh C, Cowley MJ.   +5 more
europepmc   +2 more sources

Easy-HLA: a validated web application suite to reveal the full details of HLA typing. [PDF]

Bioinformatics, 2020
International audienceMOTIVATION:The HLA system plays a pivotal role in both clinical applications and immunology research. Typing HLA genes in patient and donor is indeed required in hematopoietic stem cell and solid organ transplantation, and the MHC ...
Geffard E, Limou S, Walencik A, Daya M, Watson H, Torgerson D, Barnes KC, CAAPA, Cesbron Gautier A, Gourraud PA, Vince N.   +10 more
europepmc   +2 more sources

High-throughput high-resolution class I HLA genotyping in East Africa. [PDF]

, 2010
HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria,
Leonard Maboko, Eller, Michael, Jerome Kim, Rebecca N Koehler, Francine E McCutchan, Michael Eller, Christian T Bautista, Hoelscher Michael, Eller, Leigh Anne, Jeffrey R Currier, Currier Jeffrey R., Nelson L Michael, Michael, Nelson L., Maboko Leonard, McCutchan, Francine E., Michael Nelson L., Maboko, Leonard, Wabwire-Mangen Fred, Fred Wabwire-Mangen, Wabwire-Mangen, Fred, Eller Michael, Eric E Sanders-Buell, Sanders-Buell, Eric E., Robb Merlin L., Kijak Gustavo H., Leigh Anne Eller, Kim Jerome, Robb, Merlin L., Bautista Christian T., Anne M Walsh, Hoelscher, Michael, Kijak, Gustavo H., Michael Hoelscher, McCutchan Francine E., Kim, Jerome, Eller Leigh Anne, Merlin L Robb, Bautista, Christian T., Koehler, Rebecca N., Koehler Rebecca N., Sanders-Buell Eric E., Walsh, Anne M., Currier, Jeffrey R., Gustavo H Kijak, Walsh Anne M.   +44 more
core   +2 more sources

Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing [PDF]

, 1988
Krämer A, Herth D, von Keyserlingk H, et al. Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing. Klinische Wochenschrift.
Sommer, D., Ludwig, W. D., Hampl, Hartmut, Riecken, Ernst-Otto, Krämer, Alexander ; https://orcid.org/, Hahn, E. G., von Keyserlingk, H., Herth, D., W. -D. Ludwig, E. O. Riecken, D. Sommer, H. Hampl, A. Krämer, H. -J. Keyserlingk, E. G. Hahn, D. Herth   +15 more
core   +1 more source

HLA typing in systemic sclerosis

Reumatismo, 2011
OBJECTIVE: The aim of the study was to investigate the relationship between Systemic Sclerosis (SSc) and HLA antigens, and to correlate these antigens with the clinical manifestations of the disease. MATERIALS AND METHODS: 55 patients were stratified according a) to the cutaneous involvement b) to the positivity of Scl-70 and anticentromere antibody ...
E. Favalli, F. Ingegnoli, S. Zeni, M. Faré, F. Fantini   +4 more
openaire   +5 more sources

A Japanese Patient with Löfgren’s Syndrome with an HLA-DR12 Allele and Review of Literature on Japanese Patients [PDF]

, 2014
Sarcoidosis is a granulomatous disorder of unknown etiology, with several clinical manifestations. Löfgren’s syndrome is an acute type of sarcoidosis, characterized by the triad of arthritis, erythema nodosum, and bilateral hilar lymphadenopathy (BHL ...
Kakugawa, Tomoyuki, Hara, Shintaro, Kohno, Shigeru, Ishimatsu, Yuji, Harada, Tatsuhiko, Sakamoto, Noriho, Hayashi, Tomayoshi, Koyama, Hanako, Hara, Atsuko, Tomonaga, Masaomi, Nakashima, Shota   +10 more
core   +1 more source

HLA Typing for Deceased Donors

, 2023
Allele-level HLA typing of 60 deceased donors determined using next-generation ...
Justin Quon (16729962)
core   +1 more source

Unusual HLA Typing in Celiac Disease [PDF]

Disease Markers, 1996
n ...
GRILLO R, PETRONZELLI F, FERRANTE P, MORA B, BONAMICO, Margherita, MAZZILLI, Maria Cristina   +5 more
openaire   +4 more sources

A fault-tolerant method for HLA typing with PacBio data

, 2017
Background: Human leukocyte antigen (HLA) genes are critical genes involved in important biomedical aspects, including organ transplantation, autoimmune diseases and infectious diseases.
Chang, Chia-Jung;Chen, Pei-Lung;Yang, Wei-Shiung;Chao, Kun-Mao, 楊偉勛;陳沛隆   +1 more
core   +1 more source