Results 71 to 80 of about 282,112 (262)
, 2018 HLA typing results for AAA formation in extension study in HLA-DQB1 and HLA-DRB1 regions for both RA and HS subjects by Fisher’s exact test.
Kenneth B. Idler (5052293) +6 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou +21 more
wiley +1 more source
Advanced Science, EarlyView.We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang +15 more
wiley +1 more source
A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase [PDF]
, 2007 Background. Abacavir hypersensitivity is strongly associated with the human leukocyte antigen (HLA)–B*5701 allele; however, the cost of routine high-resolution HLA typing before initiation of therapy remains prohibitive.
Chui, C.K.S. +6 more
core
Overview of adalimumab RA and HS studies for HLA typing.
, 2018 Overview of adalimumab RA and HS studies for HLA typing.
Kenneth B. Idler (5052293) +6 more
core +1 more source
Advanced Science, EarlyView.XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao +5 more
wiley +1 more source
, 2009 Aim: HLA-matched donor search is an essential component in unrelated hematopoietic stem cell transplantation, and accuracy of registry typing (RT) of donors is important for timely search and coordination of matched donors. We analyzed discrepancies of
Chung, Hye Yoon +5 more
core
An SSP-PCR method for the rapid detection of disease-associated alleles HLA-A*29 and HLA-B*51.
, 2018 HLA-A*29 and HLA-B*51 are associated with birdshot uveitis and Behçet's disease, respectively, and are used as a diagnostic criterion in patients with suspected disease, requiring their detection in diagnostic laboratories.
Schärer, Dominic Manuel +4 more
core +1 more source
Advanced Science, EarlyView.Incomplete microwave ablation (iMWA) induced a spatially organized, macrophage‐rich immunosuppressive tumor microenvironment (TME) in orthotopic VX2 liver tumors. Molecular MRI enhanced with europium‐doped very small superparamagnetic iron oxide nanoparticles (Eu‐VSOP) noninvasively visualized this remodeling, showing preferential nanoparticle ...
Yubei He +22 more
wiley +1 more source