HLA-J, A SECOND INACTIVATED CLASS I HLA GENE RELATED TO HLA-G AND HLA-A [PDF]
Girdlestone, J. +5 more
core +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
deltaHED predicts survival and immune evasion in PD-1 blockade therapy: A multi-cohort study across three cancer types. [PDF]
Xu J +10 more
europepmc +1 more source
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah +3 more
wiley +1 more source
Steroid Phenotype Stratification Reveals Distinct HLA Expression Signatures in Adrenocortical Carcinoma. [PDF]
Giner IS +6 more
europepmc +1 more source
Association Between HLA Alleles and IgA Nephropathy in a Taiwanese Population. [PDF]
Huang YC +6 more
europepmc +1 more source
The Tübingen approach: identification, selection and validation of tumor-associated HLA peptides for cancer therapy [PDF]
Harpreet Singh +8 more
openalex +1 more source
Author Response: Morphea, Gluten, and Autoimmunity: HLA Behind the Scenes?
Mitchell Davis +3 more
openalex +2 more sources
ABSTRACT Non‐severe aplastic anemia (NSAA) is a heterogeneous bone marrow failure syndrome with limited standardized treatment options. Cyclosporine A (CsA) monotherapy often yields suboptimal responses, highlighting an unmet clinical need for more effective therapies.
Lele Zhang +18 more
wiley +1 more source
HLA-Knockout: Enabling Allele-Specific Knockout of HLA Class I Genes for Immunogenic Engineering. [PDF]
Mattivi C, Wang S, Ji L, Xiao Q, Cao J.
europepmc +1 more source

