Results 191 to 200 of about 593,053 (260)

In Silico-Identified Peptides of Five <i>Borrelia burgdorferi</i> Proteins Binding with High Affinity to Human Leukocyte Antigen (HLA) Class II Alleles. [PDF]

Biology (Basel)
Georgopoulos AP, James LM, Sanders M.
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Population HLA coverage of experimentally characterized <i>P. falciparum CD8</i> ^<i>+</i> T cell epitopes as potential components of a multi-epitope malaria vaccine construct: an <i>in silico</i> insight. [PDF]

Front Bioinform
Siame C, Abdul-Mumin R, Agyekum G, Akuffo L, Afari E, Yankey CAB, Kusi KA.   +6 more
europepmc   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

BASECAMP-1 screening study: a model for efficient enrolment in precision oncology clinical trials. [PDF]

BMJ Oncol
Hecht JR, Molina JR, Liechty K, Welling TH, Grierson PM, Patel SP, Kirtane K, Morelli MP, Locke FL, Maloney DG, Punekar SR, Nikiforow S, Lin Y, Ulrickson M, Specht JM, Lozac'hmeur A, Osterman CK, Garde RJ, Rangel GA, Ng EW, Welch JS, Tebbets JC, Go WY, Simeone DM.   +23 more
europepmc   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Believing in the Nobel Prize: Long-term Success After HLA-Identical Kidney Transplantation in 3 Monozygotic Twins Without any Induction or Maintenance Immunosuppression. [PDF]

Transplant Direct
Akifova A, Ömeroğlu ÖE, Halleck F, Osmanodja B, Schrezenmeier EV, Bachmann F, Stauch D, Lachmann N, Budde K.   +8 more
europepmc   +1 more source

Monocyte maturation pattern by flow cytometry expression of CD64, CD300e, and CD14 correlates to presence of myeloid neoplasm and helps identify blast equivalents in the setting of monocytic neoplasm

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD300e is a marker of mature monocytes in flow cytometry; however, there is limited detailed information on staining patterns in conjunction with other monocyte markers. We evaluated the flow cytometric staining patterns of CD64, CD14, and CD300e in 12 negative and 33 positive peripheral blood specimens and 16 negative and 56 positive bone ...
Jenny Zhang, Jacob Kaplan, Elizabeth Courville   +2 more
wiley   +1 more source

Vaccine strategies for cancer prevention in Lynch syndrome: the potential of dendritic cell-based therapy. [PDF]

Fam Cancer
Kuipers RN, Gorris MAJ, Bayó C, Hofland T, Ribas DB, Grau GF, Hoogerbrugge N, Castillo J, Balaguer F, Bisseling TM, Schreibelt G, de Vries IJM.   +11 more
europepmc   +1 more source