Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon +8 more
wiley +1 more source
The Expanding Role of HLA-E in Host Defense: A Target for Broadly Applicable Vaccines and Immunotherapies. [PDF]
Rafieiyan M +4 more
europepmc +1 more source
Structural evolution of polymorphic class I HLA alleles, designating HLA-C with uncertain assemblies. [PDF]
Padariya M +2 more
europepmc +1 more source
Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
wiley +1 more source
The application of genetic testing technology in kidney transplantation: precision matching, non-invasive monitoring and personalized management. [PDF]
Zhang Y +5 more
europepmc +1 more source
Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad +8 more
wiley +1 more source
Genetically Validated Immune Susceptibility Markers for Crohn's Disease: A Multi-Omics Mendelian Randomization Analysis. [PDF]
Li Z.
europepmc +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source

