Results 281 to 290 of about 676,827 (333)

Acute Rejection With DSA-Negative Severe Microvascular Inflammation in a Kidney Transplant Recipient With an Isolated DPB1*04-Mismatch Successfully Stabilised With Daratumumab. [PDF]

HLA
Knödl L, Büttner-Herold M, Götz M, Luber M, Spriewald B, Oellerich M, Beck J, Banas B, Zecher D.   +8 more
europepmc   +1 more source

Functional CRISPR‐Cas9 knockout screening of the genetic determinants of human fibroblast migration propensity

Biotechnology Progress, EarlyView.
Abstract Directional cell migration plays a central role in a wide range of physiological and pathological conditions, such as embryonic development or tumor metastasis. Steps involved in cell migration include cell polarization, formation of membrane protrusions at the cell front side and adhesion disassembly at the rear side, and a general ...
Antonio Mazzei, Sebastian Martewicz, Ramin Amiri, Meihua Cui, Nicola Elvassore, Camilla Luni   +5 more
wiley   +1 more source

Single-cell RNA transcriptomics divulged altered gene expressions in monocytes and HLA variations in decompensated cirrhosis patients with sepsis. [PDF]

Sci Rep
Sehgal R, Gautam P, Islam M, Kumar Sevak J, Javed M, Kaur N, Ramakrishna G, Maiwall R, Sarin SK, Trehanpati N.   +9 more
europepmc   +1 more source

Anatomical Study With Clinical Significance of the Buccomandibular Space: A Complementary Ultrasonographic Study to Cadaveric Dissection

Clinical Anatomy, EarlyView.
ABSTRACT The buccomandibular space is a potential space located within the oral and maxillofacial regions. This morphological study aimed to provide a detailed anatomical description and ultrasonographic examination of the buccomandibular space and its adjacent structures, to discuss its clinical significance—particularly in relation to pathological ...
Hyun‐Ju Ji, Kyu‐Lim Lee, Joe Iwanaga, Koichi Watanabe, Hyoung‐Moon Kim, Hee‐Jin Kim   +5 more
wiley   +1 more source

Mendelian randomization identifies multiple immune cell surface markers as potential causal contributors and drug targets in rheumatoid arthritis. [PDF]

J Int Med Res
Huang G, Huang Y, Liao G, Xiao K, Li C, Gu R.   +5 more
europepmc   +1 more source

Mechanisms of Resistance to Cancer Immunotherapy: A Host–Tumor Interaction Perspective; A Review Article

Cancer Nexus, EarlyView.
Mechanisms of resistance to cancer immunotherapy from a host–tumor interaction perspective. The central tumor cell is protected by multiple resistance mechanisms, including genetic mutations, epigenetic modifications, and metabolic alterations. The immunosuppressive tumor microenvironment features myeloid‐derived suppressor cells (MDSCs), regulatory T ...
Mohammed Elmujtba Adam Essa, Hamid Noori, Abdelkareem A. Ahmed   +2 more
wiley   +1 more source

B Cells Can Trigger the T-Cell-Mediated Autoimmune Response Against Melanocytes in Psoriasis. [PDF]

Cells
He M, Bernhardt M, Arakawa A, Kim SM, Vollmer S, Summer B, Arakawa Y, Ishimoto T, Schlosser A, Prinz JC.   +9 more
europepmc   +1 more source

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, Soufian Meziyerh, Dave L. Roelen, Stefan Böhringer, Teun Van Gelder, Jesse J. Swen   +10 more
wiley   +1 more source

An overview of HLA variants in COVID-19 vaccine-induced autoimmunity. [PDF]

Int J Mol Epidemiol Genet
Bouayad A.
europepmc   +1 more source