Results 21 to 30 of about 387,087 (317)

Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]

open access: yes, 1989
Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Tabaczewski, P.   +9 more
core   +1 more source

Espectro Clínico y Biomarcadores Genéticos de susceptibilidad en el síndrome de Vogt-Koyanagi- Harada en pacientes Paraguayos

open access: yesRevista Paraguaya de Reumatología, 2021
Introducción: La enfermedad de Vogt-Koyanagi-Harada (VKH) es de etiología autoinmune y severa, se manifiesta con panuveítis bilateral y puede afectar sistema neuroauditivo y piel. La influencia de los factores genéticos en la expresión de VKH, ha quedado
Nelly Colmán   +7 more
doaj   +1 more source

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]

open access: yes, 1998
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan   +14 more
core   +1 more source

HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy [PDF]

open access: yes, 2008
We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258
Battegay, Manuel   +42 more
core   +2 more sources

HLA-A, HLA-B and HLA-C Polymorphism in the Slovak Population

open access: yesFolia Biologica, 2000
The occurrence rates of class I HLA alleles were investigated in a sample of the Slovak population by a PCR-SSP method. The frequencies of HLA-A alleles ranged from 0.00 for A*4301 to 0.2798 for A*0201-22; the frequencies of HLA-B alleles ranged from 0.00 for B*4601, B*4801-3, B*5901, B*7301, and B*8101 to 0.1101 for B*4402-10, and those of HLA-C ...
E, Kulcsárová, M, Buc, S, Ferencik
openaire   +2 more sources

Indirect Scapholunate Ligament Repair: All Arthroscopic

open access: yesArthroscopy Techniques, 2018
The arthroscopic technique most frequently used in acute scapholunate instability is reduction and fixation with Kirschner wires. To repair the injured ligament, open surgery and dorsal capsular plication are recommended, but this procedure has the risk ...
David Bustamante Suárez de Puga, M.D.   +6 more
doaj   +1 more source

HLA Allele and Haplotype Frequencies in Three Urban Mexican Populations: Genetic Diversity for the Approach of Genomic Medicine

open access: yesDiagnostics, 2020
Genetic variability defends us against pathogen-driven antigens; human leucocyte antigens (HLA) is the immunological system in charge of this work. The Mexican mestizo population arises mainly from the mixture of three founder populations; Amerindian ...
Alma D. Del Angel-Pablo   +6 more
doaj   +1 more source

Tetrameric complexes of HLA-E, HLA-F, and HLA-G

open access: yesJournal of Immunological Methods, 2002
HLA-E, HLA-F, and HLA-G are human nonclassical MHC class Ib molecules. To study the function and identify potential ligands of these molecules, we constructed tetrameric complexes. In this brief review, we discuss the methods used to produce such tetramers and the interesting results they provided. HLA-E tetramers bound to natural killer (NK) cells and
Allan, D   +4 more
openaire   +3 more sources

The role of HLA-B27 in inflammatory arthritis [PDF]

open access: yes, 2009
Redacted electronic version excludes material for which permission has not been granted by the rights holderThe MHC class I allele, HLA-B27, is strongly associated with a group of inflammatory arthritic conditions collectively known as ...
Lynch, Sarah Janice
core   +2 more sources

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

open access: yes, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V.   +5 more
core   +1 more source

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