Results 291 to 300 of about 177,468 (356)

Human CD141+ dendritic cells: A unique tolerogenic subset inducing immune tolerance in systemic lupus erythematosus patients

Rheumatology &Autoimmunity, EarlyView.
Peripheral blood mononuclear cells were isolated from 12 systemic lupus erythematosus (SLE) patients and 12 healthy controls. The number and function of peripheral blood CD141+ dendritic cells (DCs) were compared between patients and controls. Moreover, the tolerogenic properties of CD141+ and CD1c+ DCs were compared in SLE patients.
Xiaodong Qin, Yujiao Wang, Yi Chen, Dong Xie, Xinran Yuan   +4 more
wiley   +1 more source

CAR-T cell therapy based on a TCR mimic nanobody targeting an intracellular antigen for solid cancers. [PDF]

Mol Ther Oncol
Lin Q, Jin S, Wang M.
europepmc   +1 more source

Enhancing Chimeric Antigen Receptor T‐Cell Generation via Microfluidic Mechanoporation and Lipid Nanoparticles

Small, EarlyView.
A high‐throughput intracellular delivery platform that integrates microfluidic mechanoporation with lipid nanoparticle‐based delivery, LNP + Squeeze, is introduced. The platform can engineer CAR‐T cells using primary human T cells with a high transfection efficiency.
Jianhua Lim, Daniel Oh, Makayla Cheng, Uday Chintapula, Shujing Liu, David Reynolds, Xiaogang Zhang, Yumeng Zhou, Xiaowei Xu, Jina Ko   +9 more
wiley   +1 more source

Prolonging calcineurin inhibitor therapy post kidney allograft failure: a prospective study. [PDF]

Ren Fail
Leal R, Fragoso P, Venda J, Gomes J, Inácio M, Guedes Marques M, Rodrigues L, Santos L, Romãozinho C, Caramelo F, Sá HO, Martinho A, Figueiredo A, Alves R.   +13 more
europepmc   +1 more source

Allospecificity of liver allograft-derived lymphocytes and correlation with clinicopathologic findings [PDF]

, 1988
Demetris, AJ, Duquesnoy, RJ, Fung, JJ, Markus, BH, Saidman, S, Starzl, TE, Zeevi, A   +6 more
core  

Exploring 2D Graphene‐Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective

Small Science, EarlyView.
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos, Nevena Todorova, Irene Yarovsky   +2 more
wiley   +1 more source

Overview on biomarkers for immune oncology drugs. [PDF]

Explor Target Antitumor Ther
Imyanitov EN, Preobrazhenskaya EV, Mitiushkina NV.   +2 more
europepmc   +1 more source

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo‐Epidermal Skin Substitutes

Small Methods, EarlyView.
This study unveils a pioneering approach to bioengineering of human skin substitutes with distinct arterial and venous capillaries. Combining single‐cell transcriptomics and 3D hydrogel models, this work reveals unique endothelial marker dynamics in fetal and juvenile skin.
Dominic Rütsche, Monica Nanni, Phil Cheng, Nicolà Caflisch, Aizhan Tastanova, Céline Jenni, Mitchell P. Levesque, Ueli Moehrlen, Agnes S. Klar, Thomas Biedermann   +9 more
wiley   +1 more source

European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN. Part 1: Definitions, Clinical Phenotypes, and Diagnostic Testing for Malabsorption

United European Gastroenterology Journal, EarlyView.
ABSTRACT Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac ...
Marco Vincenzo Lenti, Heinz Florian Hammer, Ilja Tacheci, Rosa Burgos, Stephane Schneider, Anastasiou Foteini, Aleksejs Derovs, Jutta Keller, Ilse Broekaert, Marianna Arvanitakis, Dan Lucian Dumitrascu, Oscar Segarra‐Cantón, Željko Krznarić, Juris Pokrotnieks, Gonçalo Nunes, Johann Hammer, Loris Pironi, Marc Sonyi, Cristina Maria Sabo, Juan Mendive, Adrien Nicolau, Jernej Dolinsek, Denisa Kyselova, Lucrezia Laterza, Antonio Gasbarrini, Teodora Surdea‐Blaga, Jorge Fonseca, Christos Lionis, Gino Roberto Corazza, Antonio Di Sabatino   +29 more
wiley   +1 more source

TCR-T cell therapy for solid tumors: challenges and emerging solutions. [PDF]

Front Pharmacol
He W, Cui K, Farooq MA, Huang N, Zhu S, Jiang D, Zhang X, Chen J, Liu Y, Xu G.   +9 more
europepmc   +1 more source