Results 11 to 20 of about 324,876 (288)
Loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) and a profound reduction of striatal dopamine are two hallmarks of Parkinson’s disease (PD).
M. López-Aguirre +7 more
doaj +1 more source
Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito ...
Carmen Gasca-Salas +14 more
doaj +1 more source
A framework to assess the impact of number of trials on the amplitude of motor evoked potentials
The amplitude of motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) is a common yet highly variable measure of corticospinal excitability.
Claudia Ammann +5 more
doaj +1 more source
Bevacizumab dose adjustment to improve clinical outcomes of glioblastoma
Background Glioblastoma (GBM) is one of the most aggressive and vascularized brain tumors in adults, with a median survival of 20.9 months. In newly diagnosed and recurrent GBM, bevacizumab demonstrated an increase in progression-free survival, but not ...
N. García-Romero +16 more
doaj +1 more source
Background Extracellular vesicles (EVs) are small membrane-bound vesicles which play an important role in cell-to-cell communication. Their molecular cargo analysis is presented as a new source for biomarker detection, and it might provide an alternative
N. García-Romero +12 more
doaj +1 more source
Hemogram-derived ratios as prognostic markers of ICU admission in COVID-19
Background The vast impact of COVID-19 call for the identification of clinical parameter that can help predict a torpid evolution. Among these, endothelial injury has been proposed as one of the main pathophysiological mechanisms underlying the disease ...
Sara Velazquez +8 more
doaj +1 more source
What Do We Know about Theory of Mind Impairment in Parkinson’s Disease?
Theory of mind (ToM) is a social cognitive skill that involves the ability to attribute mental states to self and others (what they think (cognitive ToM) and feel (affective ToM)). We aim to provide an overview of previous knowledge of ToM in Parkinson’s
Clara Trompeta +2 more
doaj +1 more source
El Colegio Montepríncipe trabaja en la educación de niños, niñas y adolescentes con diagnóstico de cáncer; apuesta por la no interrupción de su vida escolar en su aspecto académico y, cuando es posible, social.
Marta Fierros-Sánchez-Cuenca +4 more
doaj +1 more source
Ebstein anomaly is a congenital disease frequently associated with atrial septal defects, which can generate a right-to-left shunt, leading to systemic desaturation and right ventricular failure.We describe the case of a 68-year-old man with central ...
Leire Unzué +5 more
doaj +1 more source

