Hypomethylating agents alone or in combination with venetoclax in very elderly acute myeloid leukemia patients: less treatment, better care? [PDF]
Hypomethylating agents (HMA) alone or in combination with venetoclax (VEN) are a mainstay for disease control in elderly acute myeloid leukemia (AML). We evaluated the non-inferiority of HMA monotherapy compared to HMA/VEN combination in 227 AML patients
Francesco Tarantini +30 more
doaj +2 more sources
Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response. [PDF]
Recent information has revealed the functional diversity and importance of mitochondria in many cellular processes including orchestrating the innate immune response. Intriguingly, several infectious agents, such as Toxoplasma, Legionella, and Chlamydia,
Lena Pernas +6 more
doaj +5 more sources
Assessment of ecological fidelity of human microbiome-associated mice in observational studies and an interventional trial [PDF]
Composition and function of the gut microbiome are associated with diverse health conditions and treatment responses. Human microbiota-associated (HMA) mouse models are used to establish causal links for these associations but have important limitations.
Matthew K. Wong +10 more
doaj +2 more sources
Association between Hindfoot Moment Arm on Weightbearing CT Scans, Radiographs, and Patient-Reported Outcomes in Flexible Progressive Collapsing Foot Deformity [PDF]
Research Type: Level 4 – Case series Introduction/Purpose: Progressive collapsing flatfoot deformity (PCFD) comprises several deformities including: hindfoot valgus, forefoot abduction, medial arch collapse with medial column instability, forefoot varus,
Dwayne Carney MD +5 more
doaj +2 more sources
The Optimization of Mix Proportion of Hot Mix Asphalt for Sustainable Flexible Pavements: Experimental Study and Grey Taguchi Relational Analysis [PDF]
Most of the Indian black topped roads have been damaged due to adverse weather and heavy load distresses. Many researchers have focused on improving durability of Hot Mix Asphalt (HMA) pavements.
Samanasa Krishna Rao, P. Sravana
doaj +1 more source
Impact of Engine Oil as a Rejuvenator on the Properties of RAP Containing Asphalt Mixtures [PDF]
In order to build roads in more sustainable and environmentally friendly ways, reclaimed asphalt pavement (RAP) must be used in large quantities. Using RAP, new asphalt can be produced with a small amount of raw materials, thus reducing the energy ...
Hameed Mohammed A., Al-Hdabi Abbas
doaj +1 more source
Evaluation the Effect of Different Kind of Waste and Mineral Filler on the Fatigue Life of Asphalt Mixtures with Dissipated Energy Method [PDF]
In recent decades, with increasing in traffic load, a great portion of repair and maintenance budget is being spent on improving the pavement failure.
Gholamali Shafabakhsh +2 more
doaj +1 more source
Typical strength of asphalt mixtures compacted by gyratory compactor
Design of asphalt mixes and quality testing is influenced by the laboratory compaction procedure. Laboratory specimens must be manufactured in a way that suitably resembles field compaction for a performance test to give reliable mechanical properties ...
Rasool Dina A. +2 more
doaj +1 more source
Marshall Characteristic for Reclaimed Asphalt Pavement [PDF]
The recycling asphalt paving creates a cycle for the use of materials that improve the use of natural resources, as it reduces the use of new materials from the aggregate and asphalt, which can be a rare commodity in some areas. The increasing in the use
Ayman A. Abdul Mawjoud +1 more
doaj +1 more source
El cultivo de jitomate (Solanum lycopersicum L.), es uno de los más importantes en el sector hortícola de México; actualmente, su producción se sustenta en el uso excesivo de fertilizantes químicos. Con la finalidad de evaluar la respuesta en rendimiento
Gustavo Adolfo Sánchez-Hernández +6 more
doaj +1 more source

