Results 31 to 40 of about 54,581 (294)

Venetoclax and hypomethylating agents (HMAs) induce high response rates in MDS, including patients after HMA therapy failure [PDF]

open access: yesBlood Advances, 2020
Key Points Treatment-naive and relapsed/refractory MDS patients receiving venetoclax and HMAs have an ORR of 59% with 63% of responders proceeding to transplant. Allogeneic stem cell transplantation after treatment with venetoclax in combination with HMA is associated with prolonged survival.
Aaron D. Goldberg   +16 more
openaire   +2 more sources

Saturation mutagenesis reveals manifold determinants of exon definition. [PDF]

open access: yes, 2017
To illuminate the extent and roles of exonic sequences in the splicing of human RNA transcripts, we conducted saturation mutagenesis of a 51-nt internal exon in a three-exon minigene.
Anquetil, Vincent   +9 more
core   +2 more sources

HMA determination v1

open access: yes, 2021
This protocol is used to determine the yield of HMA producted by E. coli by using HPLC.
openaire   +1 more source

Réduction du Risque Hémorragique par Ligature Première des Artères Hypogastriques dans les Adénomectomies Prostatiques de Gros Volume

open access: yesHealth Research in Africa
RÉSUMÉ Introduction. L’adénomectomie prostatique est une intervention à haut risque hémorragique, surtout pour des hypertrophies bénignes de la prostate de haut volume.
Yao Evrard Kouamé   +7 more
doaj   +1 more source

Unifying Scaling Relations and Multiple Reaction Mechanisms for Screening Transition Metal‐Doped Co3O4 for Oxygen Evolution Reaction

open access: yesAngewandte Chemie, EarlyView.
Doped Co3O4 climbs a mechanistic volcano: transition‐metal substitution reshapes the OER activity landscape, while multiple competing reaction mechanisms govern the volcano trends across different dopants. ABSTRACT Accelerating the discovery of oxygen‐evolution reaction (OER) catalysts requires high‐throughput screening strategies combining descriptor ...
Kapil Dhaka   +7 more
wiley   +2 more sources

Photo‐Controlled Antibacterial Drug Release From DASA‐Coated Silica Particles for Improved Treatment of Wound Infections

open access: yesAdvanced Functional Materials, EarlyView.
Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc   +9 more
wiley   +1 more source

Performance of Indiana's Superpave HMA Mixtures

open access: yes, 2011
This project followed the performance of a number of hot mix asphalt paving projects for seven to eight years in an attempt to relate laboratory test results to field performance. First, a small scale study compared sampling locations, specific gravity test procedures and compaction devices used on two samples from projects, one with volumetric ...
Shah, Ayesha, McDaniel, Rebecca
openaire   +4 more sources

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Size Effects on Pumping Rates in High Microbial versus Low Microbial Abundance Marine Sponges

open access: yesOceans, 2023
Sponges are increasingly recognized as ecologically important on coral reefs as scleractinian corals decline. Most sponge species can be divided into two symbiotic phenotypes which are characterized as high microbial abundance (HMA) or low microbial ...
Michael P. Lesser
doaj   +1 more source

Study of a hot asphalt mixture response based on energy concepts [PDF]

open access: yes, 2011
The main objective of the research reported in this paper is to determine the response of a hot mix asphalt (HMA) in terms of both the tensile strength and energy parameters (based on the assessment of the force-displacement curve) as potential tools for
Alvarez Lugo, Allex E.   +2 more
core   +3 more sources

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